Three-Dimensional Analysis of Cell Division Orientation in Epidermal Basal Layer Using Intravital Two-Photon Microscopy

    September 2016 in “ PLoS ONE ”
    Sari Ipponjima, Terumasa Hibi, Tomomi Nemoto
    Studysummary The researchers reported that in hairless mice, epidermal cell division orientations and epidermal thickness varied by body site, with dorsal and ear epidermis primarily dividing parallel to the basement membrane, unlike hind paw and tail epidermis.
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    Research cited in this study 3

    1. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    2. Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration Nature · 2012
    3. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005