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Different types of cells in the eye express specific keratins at various stages of development.

Japanese researchers created new hair follicles from human cells that grew hair when put into mice, and other findings showed a link between eye disease severity and corneal thickness, gene mutations affecting hearing and touch, and the safety of the shingles vaccine for adults over 50.

The study found that males with KFSD had severe skin and eye symptoms, while female carriers had milder symptoms.

New treatments targeting specific genes show promise for treating keratin disorders.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

A new mutation in the Connexin 26 gene was found in a patient with KID syndrome, expanding the known disorders linked to this gene.

The document is a detailed guide on skin conditions and treatments for dermatologists.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

K16 can partially replace K14 but causes hair loss and skin issues.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.

Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.

A rare genetic skin condition usually affecting males was found in a 9-year-old girl.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

A patient with total hair loss developed vitiligo after using a treatment called DCP.

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.

The document explains the genetic causes and characteristics of inherited hair disorders.

The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.

The document concludes that early diagnosis and treatment are crucial for managing rare hair loss disorders and that more research is needed to improve treatment strategies.

The document concludes that different types of hair loss have specific treatments, and early diagnosis is crucial for preventing permanent hair loss.