12 citations
,
June 2022 in “International Journal of Molecular Sciences” In this study, copper was found to promote the proliferation of dermal papilla cells in Rex rabbits by maintaining the function of the cellular mitochondrial electron transport chain.
10 citations
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January 1980 in “Ultrastructural pathology” This study suggests that elevated copper levels in domestic tapwater, exacerbated by its aggressive properties, likely contribute to green hair by damaging the cuticle and increasing copper uptake.
7 citations
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January 2002 in “Biological Trace Element Research” This study found that children with pituitary dwarfism had higher zinc and copper hair concentrations and lower manganese concentrations compared to healthy children.
7 citations
,
December 2017 in “Basrah Journal of veterinary Research” This study in Basra province sheep reported that zinc and copper deficiencies were linked to various clinical signs and affected oxidative stress and antioxidant levels.
6 citations
,
February 1998 in “PubMed” This study found that patients with MPA had significantly lower zinc and manganese levels and higher copper levels in their hair compared to hair-healthy men.
6 citations
,
September 1957 in “Poultry Science” This study found that adding molybdenum to poultry diets depressed growth without affecting feather pigmentation, and copper supplementation tended to counteract the growth inhibition.
5 citations
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January 2022 in “Pesquisa Veterinária Brasileira” The study described an outbreak of copper deficiency in dairy goats and kids in Pernambuco, Brazil, leading to various clinical and reproductive issues in the animals, including enzootic ataxia in kids.
4 citations
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September 2024 in “Cureus” In this study, using a 15-day regimen combining a scalp scrub and serum significantly improved dandruff and scalp health in participants, reducing flaking, increasing hair density and thickness, and enhancing hydration and overall scalp appearance.
3 citations
,
June 2019 in “Journal of Bangladesh Society of Physiologist” This study found that patients experiencing hair loss had significantly lower serum levels of zinc and copper compared to healthy controls.
3 citations
,
February 2016 in “Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Māzandarān/Journal of Mazandaran University of Medical Sciences” This study observed that noncertified Kohl used in Iranian cities contained heavy metals within WHO suggested limits, but highlighted concerns due to high levels in some samples.
3 citations
,
May 2014 in “InTech eBooks” This review discusses the genetic and androgen-related factors in androgenetic alopecia, highlighting a specific polymorphism in the AR protein associated with male pattern hair loss, and reports no new clinical results.
2 citations
,
April 2025 in “Biomedicine & Pharmacotherapy” This research reports that copper-quercetin complexes show strong potential in antioxidation and cancer therapy, while their effects on specific cell death pathways warrant further investigation.
2 citations
,
January 2023 in “Ceramics International” In this study, the Cu-doped bioglass composite dressings showed promising results for wound healing and hair follicle regeneration in vitro, with enhanced fibroblast proliferation and vascular growth.
1 citations
,
December 2022 in “Bioactive Materials” In this study, researchers developed a nanocomposite microneedle patch containing copper/zinc dual-doped silica nanoparticles, which release substances to promote hair follicle regeneration by targeting various pathophysiological aspects of androgenic alopecia, presenting an effective anti-hair loss treatment strategy.
1 citations
,
February 2022 in “Open Access Macedonian Journal of Medical Sciences” This study found that lower zinc serum levels may contribute to premature hair graying in college students at Universitas Sumatera Utara.
1 citations
,
January 2016 in “American Journal of Clinical and Experimental Medicine” This study found that men with androgenic alopecia had significantly different hair copper levels compared to controls, but no difference in blood copper levels between the groups was observed.
August 2024 in “Journal of Cosmetic Dermatology” This study investigates differences in nutritional status, vitamin, and mineral levels between individuals with telogen effluvium and a control group, aiming to understand the nutritional factors involved in this condition.
June 2024 in “Journal of Islamic International Medical College” This study evaluated serum copper and zinc levels in individuals with various types of alopecia and found that low zinc levels are associated with all types of alopecia, while low copper levels are specifically related to male pattern hair loss.
June 2024 in “Research Square (Research Square)” This study found that women experiencing hair loss post-COVID-19 showed significantly decreased serum copper levels, suggesting potential further research into copper supplementation for preventing and treating post-COVID-19 alopecia.
May 2024 in “Pakistan Journal of Health Sciences” This study found that people with chronic telogen effluvium had lower hair and serum iron levels and higher serum copper levels compared to healthy controls.
March 2024 in “International journal of molecular sciences” This study suggests that abnormal levels of zinc, copper, and iron in serum or hair may serve as auxiliary and prognostic tests for various skin diseases, though further research is necessary due to conflicting data.
December 2023 in “Archives of iranian medicine” This study used hair samples to assess mineral levels and found that higher iron status may be associated with an increased risk of esophageal squamous cell carcinoma, while no significant associations were observed for copper and magnesium levels in this cohort.
November 2023 in “Biology” This study investigated 130 patients and found a significant inverse correlation between copper content and the copper/zinc ratio in hair samples and the extent of coronary artery disease, while zinc content alone showed no significant relationship with disease extent.
April 2023 in “Acta Poloniae Pharmaceutica” This study found that using Urtica cannabina extract shampoo led to increased levels of copper, zinc, and iodine in the scalp hair of Mongolian women, along with improvements in hair growth, diameter, and density compared to a regular shampoo.
December 2022 in “Himi, himijn tehnologijn hùrèèlèngijn èrdèm šinžilgèènij bùtèèl” This study found that using the "Khalgai" hair care products enriched with copper and zinc for 28 days led to increased hair density, diameter, and follicular unit count in women, indicating improved hair morphology.
February 2021 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that women with telogen effluvium had significantly lower serum copper and zinc levels compared to controls, suggesting these deficiencies may be associated with the condition.
October 2014 in “Journal of Nutrition & Food Sciences” This study found that in visceral-obese Korean adults, hair chromium and selenium levels were inversely associated with insulin resistance, while copper levels showed a positive association.
January 2004 in “Trace Elements Science” This study observed that hair levels of chromium, manganese, and copper were lower in diabetics compared to controls, while iron levels were higher.
January 1992 in “Journal of Oriental Neuropsychiatry” This study found that zinc, copper, and chromium levels were significantly lower in the hair of Korean individuals with schizophrenia compared to healthy individuals.
March 1963 in “Sangyo Igaku” Women generally have higher levels of iron, copper, and zinc in their hair than men, with differences increasing with age.