Iron, Copper, and Magnesium Concentration in Hair and Risk of Esophageal Cancer: A Nested Case-Control Study

December 2023 in “ Archives of iranian medicine ”

Maryam Hashemian, Hossein Poustchi, Maryam Sharafkhah, Akram Pourshams, Fatemeh Mohammadi‐Nasrabadi, Azita Hekmatdoost, Reza Malekzadeh

iron copper magnesium hair samples inductively coupled plasma mass spectrometry ICP-MS

TLDR Higher iron levels in hair may increase the risk of esophageal cancer.

This nested case-control study within the Golestan Cohort Study examined the association between iron, copper, and magnesium concentrations in hair samples and the risk of esophageal squamous cell carcinoma (ESCC). The study included 96 incident ESCC cases and matched cancer-free controls. Using inductively coupled plasma mass spectrometry (ICP-MS), the researchers found that higher iron concentrations in hair were significantly associated with an increased risk of ESCC (OR=1.41, 95% CI=1.03-1.92). However, no significant associations were observed for copper and magnesium concentrations. The findings suggest that higher iron status may be related to a higher risk of ESCC in this population.

View this study on doi.org →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Development of a Predictive Model for Iron Levels in Bovine Muscle Tissue Using Hair as a Predictor

March 2024 in “Animals”

Hair can accurately predict iron levels in cattle muscle, helping diagnose mineral imbalances.

research Zinc, Copper, and Iron in Selected Skin Diseases

March 2024 in “International journal of molecular sciences”

Zinc, copper, and iron are important for skin health and may help diagnose skin diseases.

research Hair Analysis in Health Assessment

84 citations, February 2013 in “Clinica chimica acta”

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

research Retrospective Diagnosis of Intrauterine Diselementosis in Newborn Calves

January 2022 in “Bio web of conferences/BIO web of conferences”

The conclusion is that normal trace element levels in newborn calves' hair are between the 25th and 75th percentiles, and levels outside this may indicate diselementosis.

Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects

research Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects

January 2024 in “Biological trace element research”

Isotretinoin affects trace element levels and requires monitoring of liver and kidney functions.

Iron, Copper, and Magnesium Concentration in Hair and Risk of Esophageal Cancer: A Nested Case-Control Study

Related Community Posts Join

community AMA: I travelled to Turkey to get an FUE Hair Transplant: 5000 Grafts, Dr Koray Erdogan, ASMED Clinic

community My Vitamin D (25-0H) levels came <4.20 ng/ml (<20 implies deficiency)and B12 came 184 pg/ml (Should be between 211-911). I have a lot of dandruff. The derm has prescribed me with 60k vitamin d tablet once a week and multivitamins for a month. Vitamin deficiency implies TE no? or is it MPB?

community Vitamin D deficiency strongly correlates with androgenic alopecia, FMPH and telogen effluvium

community I'm tired, boss. I fought. Now I seem to be losing.

community Increased Coffee intake resulted in massive shed