51 citations
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October 2024 in “Pharmaceutics” This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.
32 citations
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June 2024 in “Pharmaceutics” This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.
17 citations
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May 2025 in “MedComm” This review highlights how organoid technology is transforming precision medicine by summarizing its development and applications in modeling diseases, testing drug efficacy, and tailoring patient-specific treatments, despite current challenges in standardization and ethical considerations.
12 citations
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January 2022 in “International Journal of Clinical Practice” This study found that women with PCOS, especially those who are obese, showed higher oxidative stress and decreased antioxidant levels, correlating with metabolic syndrome and cardiovascular disease risk factors.
5 citations
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April 2024 in “BMJ Open” This scoping review revealed that methods for measuring traumatic scar thickness using ultrasound are inconsistently reported and mainly remain in early research phases, highlighting a need for standardizing these methods to bridge the gap to routine clinical practice.
5 citations
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January 2025 in “Burns & Trauma” This review highlights recent research using single-cell RNA sequencing and machine learning in wound healing, revealing significant insights into fibroblast diversity, immune cell dynamics, and the spatial organization of cells, which may transform therapeutic strategies for chronic wounds, fibrosis, and tissue regeneration.
1 citations
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August 2024 in “Polish Journal of Environmental Studies” This study reviewed 54 articles to examine how continuous exposure to air pollution causes hair damage, hair loss, and scalp conditions due to oxidative stress and inflammation, and highlighted anti-inflammatory substances that could mitigate these effects.
1 citations
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December 2022 in “Gynecological Endocrinology” This study found that among women with PCOS, higher HOMA-IR levels were associated with acanthosis nigricans, and increased DHEA-SO4, FAI, and FI values were linked to hirsutism.
May 2026 in “Cell Reports Medicine” This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.
October 2024 in “Irish Journal of Medical Science (1971 -)” Continuous glucose monitoring and GLP-1 receptor agonists improve diabetes management, but personalized care and education are crucial.
This review discusses forensic DNA phenotyping and its potential applications, particularly for human identification in Latin American populations, but notes challenges due to genetic diversity and reports no new results.
September 2023 in “Membranes” This source reviews the potential of 3D printing, biomaterials, and smart sensors in tissue engineering, noting their application in creating artificial membranes for skin and tissue regeneration and assessing their strengths and limitations for wound dressing development and disease modeling.
August 2023 in “Military Medical Research” This review highlights that skin organoids, advanced three-dimensional models mimicking human skin, are emerging as effective alternatives to traditional culture models and human skin, overcoming limitations of two-dimensional systems and ethical concerns, and are being increasingly used in areas like developmental biology and disease modeling.
321 citations
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December 2009 in “Journal of Dermatological Science” This review discusses the role of dermal cells in hair follicle regeneration and morphogenesis and highlights their potential therapeutic implications, but it reports no new empirical findings.
126 citations
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August 2018 in “Molecular Systems Biology” This study found that in murine dermis, fibroblast state switching between proliferation and ECM deposition plays a crucial role in tissue architecture and wound healing.
28 citations
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April 2021 in “Biomedicines” This review evaluates in vitro hair follicle models, techniques, and challenges without reporting new clinical results, emphasizing their future potential in hair transplantation.
169 citations
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January 2018 in “Cell Reports” In this study, researchers successfully derived skin organoids from mouse pluripotent stem cells that spontaneously produce hair follicles, potentially aiding in hair growth research and in vitro drug testing.
81 citations
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October 2023 in “Bioactive Materials” This review highlights the promising potential of 3D printing for creating microneedles with precise customization and improved performance compared to traditional micromolding, emphasizing applications in personalized medical devices and advancements in biomedical fields.
38 citations
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December 2009 in “Therapeutic Advances in Medical Oncology” This discussion proposes a model to incorporate patients with hormone-resistant prostate cancer into the existing framework by redefining hormone resistance and exploring new therapeutic approaches.
25 citations
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February 2023 in “Aesthetic Surgery Journal” This review concludes that current clinical and preclinical evidence does not indicate oncologic safety concerns linked to photobiomodulation therapy for skin rejuvenation, including no clear evidence of increased cancer risk.
25 citations
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April 2021 in “The EMBO Journal” This review discusses the role of hair follicle stem cells as active signaling centers in skin homeostasis, highlighting recent advancements and reporting no new clinical results.
25 citations
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January 2009 in “Oral and Maxillofacial Surgery Clinics of North America” This article reviews complications associated with modern hair transplant surgery and discusses their treatment and prevention but reports no new clinical results.
17 citations
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July 2024 in “Advanced Intelligent Systems” This review explores the complexity of human–robot interactions in robotic surgery, finding that complexity increases with conditional autonomy and is predicted to decrease with full autonomy, without reporting new clinical results.
11 citations
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October 2022 in “Clinical Cosmetic and Investigational Dermatology” In this study, SNPs in genes affecting skin pigmentation were linked to each skin type's unique response to environmental stress, suggesting potential for personalized skin care products.
May 2026 in “The EMBO Journal” This study demonstrated how cellular flows and tissue mechanics guide the topological transformations in avian skin, essential for feather follicle development from scales.
July 2026 in “Journal of Medicinal Chemistry” In this study, candidate compound 39 demonstrated potent androgen receptor antagonism and faster hair-growth efficacy in a mouse model compared to pyrilutamide, while maintaining favorable safety and pharmacokinetic profiles, suggesting potential for topical use in androgenic alopecia.
November 2025 in “Cureus” This study found that COVID-19 vaccines were generally well-tolerated among Bangladeshi medical students, with most side effects being mild and decreasing in frequency after subsequent doses.
May 2025 in “Frontiers in Pharmacology” This review reports that while current treatments for non-scarring alopecia, like minoxidil and finasteride, have limited efficacy due to side effects, natural remedies may offer more effective management with potentially fewer side effects, though their varying safety profiles call for further investigation.
January 2023 in “Pharmaceutics” In this study, researchers developed a new topical atraric acid formulation, AA-TF#15, which showed a significantly higher drug penetration and increased hair regrowth in mice compared to minoxidil and finasteride treatments, suggesting its potential effectiveness for treating scalp androgenic alopecia.
June 2021 in “Cosmoderma” This source reviews the latest developments in hair transplantation for androgenetic alopecia, suggesting that while medical therapy alone remains unsatisfactory, surgical hair restoration is shown to be highly gratifying for male pattern hair loss.