30 citations
,
September 2017 in “Clinics in Dermatology” This review explores the relationship between androgenetic alopecia and metabolic syndrome, suggesting an association that supports considering cardiovascular risk assessments in patients with this type of hair loss.
30 citations
,
October 2010 in “Journal of The American Academy of Dermatology” This review examines the debated link between iron deficiency and nonscarring scalp alopecia in women, offering no new clinical results but emphasizing the need for further research and well-designed trials.
28 citations
,
February 2014 in “Journal of Cutaneous Pathology” In this study, researchers observed that keratoacanthoma exhibits dynamic follicular differentiation throughout its stages, with changes in specific keratin expressions, and regressed lesions showing epidermal rather than follicular characteristics.
27 citations
,
August 2010 in “Clinics in Dermatology” This article reviews the association between hepatitis C virus and systemic disorders like mixed cryoglobulinemia, highlighting potential autoimmune side effects from interferon-a2b treatments, and reports no new clinical results.
26 citations
,
July 2011 in “PubMed” The authors report a case where alopecia areata went into remission after H. pylori eradication, suggesting a potential link that could expand treatment options if further studies confirm it.
23 citations
,
May 2017 in “Journal of the American Academy of Dermatology” This study found that patients with frontal fibrosing alopecia had lower epidermal melanocyte counts and reduced epidermal thickness compared to lichen planopilaris patients and controls, suggesting a link with hypopigmentation.
23 citations
,
March 2010 in “Medical hypotheses” This review explores potential new roles for Merkel cells, including involvement in magnetoreception, fingerprint formation, and transmitting environmental information, but reports no experimental results.
22 citations
,
March 2009 in “Journal of Natural Medicines” This study found that Erica multiflora extract promotes hair growth by enhancing dermal papilla cell activity and shifting hair follicles from the telogen to the anagen phase in both in vitro and in vivo models.
22 citations
,
September 2008 in “International Journal of Dermatology” This case report describes a 41-year-old woman with segmental vitiligo and lichen sclerosus in the perineal region, where treatment with clobetasol ointment improved repigmentation and resolved many symptoms, although some scaling persisted.
22 citations
,
April 2006 in “Journal of The American Academy of Dermatology” This review discusses the diagnosis and treatment of iron deficiency, its potential link to hair loss, and emphasizes the importance for dermatologists to understand these aspects; it reports no new findings.
22 citations
,
August 2002 in “The American Journal of Medicine” Atorvastatin may cause hair loss in some people.
20 citations
,
November 2002 in “Journal of the European Academy of Dermatology and Venereology” Lichen planopilaris may be linked to autoimmune thyroiditis.
19 citations
,
September 2019 in “PLOS genetics” This study found that telomere shortening disrupts BMP/pSmad/P63 signaling, leading to skin atrophy via Follistatin up-regulation, and suggests potential therapeutic targets.
18 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
16 citations
,
January 2012 in “Indian Journal of Endocrinology and Metabolism” This case series describes six women with both PCOS and Graves' disease, suggesting a possible shared underlying cause for their co-occurrence.
16 citations
,
September 1997 in “Oral surgery, oral medicine, oral pathology, oral radiology and endodontics” This case analysis suggests that while dental foci may rarely contribute to alopecia areata, confirming this link requires observing full recovery after removing the dental cause.
15 citations
,
January 2015 in “Dermatology Research and Practice” This study found no significant association between androgenetic alopecia and metabolic syndrome, though systolic blood pressure was higher in the alopecia group compared to controls.
14 citations
,
January 2008 in “Dermatology” This review discusses the role of vitamin D metabolism in skin immunity and wound healing but does not present new results, highlighting the need for further research into its therapeutic applications.
13 citations
,
August 2005 in “Dermatologic Clinics” This article reviews milestones in understanding psychosomatic factors in dermatology and outlines clinical criteria for identifying them, but it presents no new research data.
13 citations
,
January 1987 in “Dermatology” This study observed that the active metabolite minoxidil sulfate promotes vascular relaxation by enhancing potassium permeability, which may inform understanding of minoxidil's antihypertensive and hair growth effects.
13 citations
,
July 1978 in “Journal of comparative pathology” In this study, feeding albino mice various doses of Acanthospermum hispidum shoots and seeds caused toxicity and death within 9 to 172 days.
12 citations
,
July 2021 in “Scientific Reports” This study found that exogenous glutamic acid can promote hair growth and keratinocyte proliferation, suggesting a novel signalling pathway in the skin.
12 citations
,
January 2014 in “Annals of Dermatology” This study found an association between hydroxyl radical-modified SOD and alopecia areata, suggesting these modifications may lead to antibody induction in the condition.
12 citations
,
July 1957 in “Journal of Investigative Dermatology” This historical observation found that parathyroid extract treatment in newborn rats led to a condition resembling scleroderma, characterized by skin hardening, calcium deposition, and possible necrosis.
11 citations
,
January 2015 in “Skin pharmacology and physiology” In this study, oral collagen peptides increased certain gene expressions related to epidermis development and the hair cycle in hairless mice skin, suggesting potential links to hair health.
11 citations
,
January 2011 in “Indian Dermatology Online Journal” This article discusses a proposed molecular mechanism linking dietary factors to acne but reports no new clinical findings.
9 citations
,
August 2015 in “Tissue Engineering and Regenerative Medicine” In this study, human dermal stem/progenitor cell-derived conditioned medium was found to promote hair regrowth in mice, possibly through effects on the Wnt/β-catenin pathway.
9 citations
,
August 2006 in “American Journal of Psychiatry” This case report suggests that lamotrigine treatment may be associated with hair loss as a rare side effect, based on the observation of hair regrowth after discontinuation of the drug in a single patient.
9 citations
,
January 2006 in “American Journal of Clinical Dermatology” This study found that Malassezia carriage was significantly more common among participants experiencing hair shedding, suggesting a potential link between this fungal presence and hair loss.
8 citations
,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” Skin health and diseases are closely linked to metabolic processes.