June 2026 in “British Journal of Dermatology” This study reviewed human evidence on the effects of 5α-reductase inhibitors, finasteride and dutasteride, on semen parameters and gonadotrophins, finding finasteride causes mild, reversible changes, while dutasteride may lead to more pronounced and potentially less reversible impacts, suggesting caution for those planning to conceive.
October 2025 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” This study found that Myoinositol and D-chiro inositol treatment improved fertility outcomes in women with PCOS, particularly in Phenotypes A and D, but larger studies are needed to confirm these results.
May 2025 in “Egyptian Journal of Dermatology and Venerology” This study found that specific SNPs in the CYP19A1 gene were associated with Female Pattern Hair Loss in Egyptian women, with altered CYP19A1 gene expression and higher frequencies of related genotypes observed in patients compared to controls.
October 2022 in “Pakistan Journal of Medicine and Dentistry” This article discusses the skin's role as both a protective barrier and a major source of antioxidants, noting its vulnerability to infections and systemic manifestations, but reports no new clinical findings.
January 2009 in “Springer eBooks” The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.
September 2008 in “Fertility and Sterility” This study found that infertile couples who perceive themselves as having high intimacy report better subjective health, particularly in fulfilling social responsibilities and maintaining physical fitness.
This article discusses various potential causes of hair loss in women undergoing renal replacement therapy and emphasizes the importance of thorough patient evaluation, but it reports no new research findings.
December 2020 in “Skin appendage disorders” This study describes a 17-year-old male with Klinefelter syndrome who developed androgenetic alopecia and showed a good response to treatment with oral minoxidil, finasteride, and low-level light therapy.
This study found that Anovlar effectively reduced pain in severe dysmenorrhea cases and regulated cycles in oligomenorrhea patients, but some side effects and occasional treatment failures were reported.
308 citations
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September 2010 in “Nucleic acids research” This study found that induced expression of mir-302 can reprogram human hair follicle cells into induced pluripotent stem cells through a novel epigenetic mechanism involving global demethylation.
186 citations
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July 1998 in “Journal of Cutaneous Medicine and Surgery” This study found that shorter CAG-repeat lengths in the androgen receptor may be associated with the development of androgen-mediated skin disorders like androgenetic alopecia, acne, and hirsutism in both men and women.
176 citations
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May 2020 in “Dermatologic Therapy” This review discusses the cutaneous symptoms associated with COVID-19 and their potential use in diagnosing and assessing the severity of the disease, but it reports no new clinical results.
144 citations
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March 2013 in “Circulation Research” This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.
98 citations
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December 2008 in “Journal of Investigative Dermatology” This review discusses the possible impacts of prolactin on skin conditions like psoriasis, alopecia, and stress-related dermatoses, emphasizing the need for further research to explore its therapeutic potential.
97 citations
,
April 2016 in “Andrology” This review discusses the etio-pathogenetic factors in benign prostatic hyperplasia and their role in the development of lower urinary tract symptoms but reports no new research findings.
93 citations
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March 2017 in “Molecular Plant” This study concluded that CNGC14 is a calcium-permeable channel crucial for polarized tip growth in Arabidopsis root hairs, but other channels may also influence the observed calcium influx.
92 citations
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January 2012 in “International Journal of Biological Sciences” This article proposes an updated naming system for keratin-associated proteins and genes, aiming to improve data storage and retrieval by including species information and genetic variation.
73 citations
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April 2019 in “Experimental Dermatology” This review explores the hair follicle microbiome's interaction with the immune system, discussing its potential clinical implications for scalp health and disease but reports no new clinical results.
73 citations
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January 2013 in “European journal of dermatology/EJD. European journal of dermatology” This review examines current research on antioxidants in autoimmune skin diseases like alopecia areata and vitiligo, concluding with suggestions for future studies and treatment possibilities without reporting new clinical results.
69 citations
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May 2009 in “Journal of Investigative Dermatology” This research highlights that psychological stress can adversely affect hair growth in mice, implicating potential pathways that may be relevant in understanding stress-induced hair growth inhibition in humans.
69 citations
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February 1983 in “Gut” This study found that untreated men with coeliac disease exhibited androgen resistance, potentially linked to sexual dysfunction, which improved as intestinal health improved, a pattern not observed in other chronic illnesses.
60 citations
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November 2013 in “Development” This study found that the creation of hair follicle lumens in mice is driven by the outward migration of keratin 79-positive cells, suggesting a novel mechanism for generating hollow cores in hair follicles.
51 citations
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May 2004 in “American journal of ophthalmology” This study reports that poliosis can be an adverse effect of topical prostaglandin F2α analog therapy in patients treated for primary open angle glaucoma.
46 citations
,
February 2016 in “Experimental Dermatology” This review discusses the genetic research developments in androgenetic alopecia, reporting no new clinical results, and highlights the potential for discovering novel therapeutic targets.
46 citations
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May 2012 in “Molecular and Cellular Endocrinology” In this study, higher expression levels of aromatase and steroidogenic acute regulatory protein were correlated with increased estrogen synthesis and fewer hair follicles in human skin, suggesting a link to elastic fiber formation and hair growth.
45 citations
,
April 2021 in “Current Treatment Options in Oncology” This review discusses cardiovascular risks associated with androgen deprivation therapy in prostate cancer patients and highlights ongoing research, including the potential reduced COVID-19 susceptibility, but reports no new results.
40 citations
,
October 2020 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” This review discusses the potential role of androgens in increasing susceptibility to severe COVID-19 complications in men but presents no new clinical findings.
40 citations
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May 2016 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that the mechanical stiffening of the human hair follicle along the first millimeter is linked to changes in the keratin network architecture and composition during keratinization.
33 citations
,
June 2012 in “Journal of Crohn's and colitis” This review discusses the role of immune responses, especially Th1 cytokines, in alopecia areata pathogenesis and reports no new research findings.
31 citations
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December 2016 in “Anais Brasileiros de Dermatologia” This review discusses the fibrogenic effects of TGFβ1, the regulatory role of PPAR, and the potential involvement of DHEA in frontal fibrosing alopecia, but reports no new clinical results.