The Role of Androgens in COVID-19

    Fatemeh Moradi, Behnaz Enjezab, Akram Ghadiri-Anari
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    TLDR Higher androgen levels might make COVID-19 worse, especially in men.
    The document discussed the role of androgens in COVID-19, highlighting that androgens might influence the severity of the disease. It suggested that higher androgen levels could be linked to increased expression of TMPRSS2, a protein that facilitates SARS-CoV-2 entry into cells. This connection could explain why men, who generally have higher androgen levels, experienced more severe COVID-19 outcomes compared to women. The study emphasized the need for further research to explore androgen-targeted therapies as potential treatments for COVID-19.
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      community Adrogens and Covid-19

      in Treatment  7 upvotes 5 years ago
      The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.

      community Affordable anti androgens in India?

      in Treatment  4 upvotes 4 months ago
      The conversation discusses hair loss treatments, specifically the use of anti-androgens like RU58841 and Pyrilutamide, which are expensive in India. Alternatives like spironolactone and concerns about the effectiveness of finasteride and dutasteride are also mentioned.

      community Overwhelming amount of anti-androgens

      in Female 2 years ago
      The conversation discusses the effectiveness of anti-androgens for hair loss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.

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