The Role of Androgens in COVID-19
October 2020
in “
Diabetes and Metabolic Syndrome: Clinical Research and Reviews
”
TLDR Higher androgen levels might make COVID-19 worse, especially in men.
The document discussed the role of androgens in COVID-19, highlighting that androgens might influence the severity of the disease. It suggested that higher androgen levels could be linked to increased expression of TMPRSS2, a protein that facilitates SARS-CoV-2 entry into cells. This connection could explain why men, who generally have higher androgen levels, experienced more severe COVID-19 outcomes compared to women. The study emphasized the need for further research to explore androgen-targeted therapies as potential treatments for COVID-19.