Evaluating Combined Therapy With Myoinositol and D-Chiro-Inositol in Infertility Management Across PCOS Phenotypes: A Comprehensive Retrospective Data Analysis
October 2025
in “
International Journal of Reproduction Contraception Obstetrics and Gynecology
”
TLDR The combined therapy improved fertility in women with PCOS, especially in certain types.
This study analyzed the effects of Myoinositol and D-chiro inositol on fertility outcomes in 200 women with PCOS, categorized into four phenotypes. The treatment, administered in a 40:1 ratio, resulted in an overall pregnancy rate of 70.6%. Phenotypes A and D showed pregnancy rates of 70.4% and 69.1%, respectively, while Phenotypes B and C achieved 100% conception rates, though these results were limited by small sample sizes. The findings suggest that this combined therapy is effective in enhancing fertility, particularly in Phenotypes A and D, but further research with larger samples is needed to confirm these results and optimize treatment protocols for different PCOS phenotypes.