research PPAR-γ Modulation as a Novel Therapeutic Strategy for Scarring Alopecia
A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.
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research Single-Cell Transcriptomic Analysis of Small and Large Wounds Reveals the Distinct Spatial Organization of Regenerative Fibroblasts
Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.
research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
research A Guide to Studying Human Hair Follicle Cycling In Vivo
The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research Ectodysplasin Research: Where to Next?
Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
research The Transcriptional Landscape of Seasonal Coat Color Moult in the Snowshoe Hare
Researchers found genes that control hair color and growth change before the visible coat color changes in snowshoe hares.
research Unveiling the Roots of Monogenic Genodermatoses: Genotrichoses as a Paradigm
New gene identification techniques have improved the understanding and classification of inherited hair disorders.
research Comparative Transcriptomic Analysis of Dermal Wound Healing Reveals De Novo Skeletal Muscle Regeneration in Acomys Cahirinus
The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
research Expanding the Clinical and Mutational Spectrum of Recessive AEBP1-Related Classical-Like Ehlers-Danlos Syndrome
The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.
research Structural and Dynamic Insights into Substrate Binding and Catalysis of Human Lipocalin Prostaglandin D Synthase
The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.
research Insights into the Regeneration of Skin from Acomys, the Spiny Mouse
The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.
research Deciphering Principles of Morphogenesis from Temporal and Spatial Patterns on the Integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Short-Term Responses of Soybean Roots to Individual and Combinatorial Effects of Elevated CO2 and Water Deficit
Elevated CO2 can lessen the negative impact of water shortage on soybean roots and affects specific genes.
research Structure Optimization of Tetrahydropyridoindole-Based Aldose Reductase Inhibitors Improved Their Efficacy and Selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research An Efficient, Non-Invasive Approach for In Vivo Sampling of Hair Follicles: Design and Applications in Monitoring DNA Damage and Aging
A new painless method to collect hair follicles helps study DNA damage and aging.
research Systems Approach to Human Hair Fibers: Interdependence Between Physical, Mechanical, Biochemical, and Geometric Properties of Natural Healthy Hair
Hair properties are interconnected; a comprehensive, cross-disciplinary approach is essential for understanding hair behavior.
research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery
A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
research Differentiation of Human Dermal Mesenchymal Stem Cells into Cardiomyocytes by Treatment with 5-Azacytidine: Concept for Regenerative Therapy in Myocardial Infarction
Skin stem cells were turned into heart cells using a chemical, suggesting a new way to treat heart attacks.
research Revisiting the Significance of Keratin Expression in Complex Epithelia
Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
research CD201+ Fascia Progenitors Choreograph Injury Repair
CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.
research Molecular and Spatial Design of Early Skin Development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research A Microscopy-Based Small Molecule Screen in Primary Neurons Reveals Neuroprotective Properties of the FDA-Approved Anti-Viral Drug Elvitegravir
The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.
research Genetic Variations Associated With Response to Dutasteride in the Treatment of Male Subjects With Androgenetic Alopecia
Genetic variations affect dutasteride treatment response for male pattern hair loss.
research The SYP123-VAMP727 SNARE Complex Is Involved in the Delivery of Inner Cell Wall Components to the Root Hair Shank in Arabidopsis
The SYP123-VAMP727 complex is important for transporting materials that harden the root hair shank in Arabidopsis.
research Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)
Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
research Convergent Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
research A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Researchers developed a new, precise method to measure hair loss in mice using image analysis.
research Reimagining Hair Science: A New Approach to Classify Curly Hair Phenotypes via New Quantitative Geometrical and Structural Mechanical Parameters
A new system for classifying curly hair types using precise measurements can improve hair care products and cultural inclusion.
research Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)
The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.