April 2023 in “IntechOpen eBooks” Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
January 2023 in “International Journal of Molecular Sciences” Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.
Reviewers criticized the study for assuming drugs with similar side-effects work the same way and questioned the validity of its findings due to potential biases and data quality issues.
Three Indian medicinal plant compounds help hair growth.
January 2010 in “Yearbook of Endocrinology” Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
July 2003 in “Journal of Cutaneous Medicine and Surgery” High blood pressure drugs often cause skin lupus, stopping the drug usually helps. A vaccine helps prevent genital herpes and HPV-16. More frequent light therapy clears psoriasis faster. No link was found between low iron and chronic hair loss.
January 2000 in “Expert Opinion on Therapeutic Patents” The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.
December 1998 in “Acta Crystallographica Section C-crystal Structure Communications” A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.
January 1989 in “Handbook of experimental pharmacology” Drugs can change hair growth and this is important because it can upset people.
April 2023 in “European urology open science” Urologists should screen for mental health issues before and during finasteride treatment.
December 2022 in “International Journal of Molecular Sciences” Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.
295 citations,
September 2006 in “Cell Cycle” The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
125 citations,
May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
115 citations,
August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Modulating Cytochrome P450 activity could help develop new skin disease treatments.
105 citations,
August 2010 in “Pharmacology & therapeutics” Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
62 citations,
December 2013 in “Aaps Journal” Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.
54 citations,
November 1998 in “Archives of dermatology” Avoiding certain nutrients and drugs may help manage pemphigus.
53 citations,
June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
51 citations,
March 2006 in “Bioorganic & Medicinal Chemistry” Newly made nicotinamide compounds could potentially treat cancer.
51 citations,
January 2001 in “Biological & Pharmaceutical Bulletin” The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.
33 citations,
June 1995 in “International journal of legal medicine” Environmental factors can greatly reduce drug levels in hair.
32 citations,
June 2015 in “PLOS ONE” Olive leaf compound oleuropein helps grow hair in mice.
23 citations,
November 2015 in “Phytotherapy Research” Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.
21 citations,
January 2003 in “Seminars in reproductive medicine” The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
20 citations,
June 2014 in “Pharmaceutical research” Using both hyaluronic acid compounds together improves skin hydration and reduces wrinkles better than using one alone.
13 citations,
February 2018 in “Bio-medical Materials and Engineering” Minoxidil inside tiny particles can deliver more drug to hair follicles, potentially improving treatment for hair loss.
13 citations,
December 2013 in “Chemistry Central Journal” Sunlight exposure increases drug toxicity; amber glass best for protection.
12 citations,
April 2016 in “Chinese Medicine” The research identified 12 antioxidant compounds in Polygonum multiflorum roots, suggesting these as quality markers for the plant's processed roots.
12 citations,
March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
12 citations,
March 2017 in “Medicinal Chemistry Research” Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.