January 2011 in “Yearbook of Dermatology and Dermatologic Surgery” The adapalene-benzoyl peroxide gel works better and faster for acne treatment than using either ingredient alone, with manageable side effects.
November 2024 in “Journal of the Philippine Dermatological Society” In this case report, significant hair regrowth was achieved in a young Filipino woman with severe diffuse alopecia areata using a combination of corticosteroids and methotrexate, highlighting the value of traditional therapies in regions with limited access to newer treatments.
July 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” This pilot clinical trial observed that combining subcision using a blunt cannula with platelet-rich plasma injections and microneedling for post-acne rolling scars was associated with a significant positive correlation between physician satisfaction and age of acne onset.
61 citations
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January 2007 in “Indian Journal of Dermatology Venereology and Leprology” This study found that garlic gel significantly improved the efficacy of topical betamethasone valerate in treating alopecia areata compared to placebo.
January 2016 in “Indian Journal of Paediatric Dermatology” This study found that a combination treatment using oral and topical steroids with topical minoxidil was well-tolerated in children with severe recalcitrant alopecia areata, showing good responses except in alopecia universalis cases.
36 citations
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June 1990 in “Archives of Dermatology” This study found that combination therapy with 5% minoxidil and 0.5% anthralin led to hair regrowth in some patients with severe treatment-resistant alopecia areata, but also caused mild to moderate irritant dermatitis in all participants.
7 citations
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April 2017 in “Dermatologic surgery” This study concluded that bimatoprost 0.03%, applied either twice or once daily, is safe, well-tolerated, and effective in improving eyebrow fullness and darkness in individuals with eyebrow hypotrichosis.
21 citations
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January 2007 in “Australasian Journal of Dermatology” This case report describes how a 53-year-old woman with female pattern hair loss experienced further hair regrowth when topical minoxidil was added to her spironolactone treatment after initial results plateaued.
March 2018 in “European Urology Supplements” Patients follow treatment well, but many change medicines; good information helps compliance.
3 citations
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January 2020 in “Acta veterinaria indonesiana” In this case study, a Persian cat with dermatophytosis showed a reduction in skin lesions after being treated with oral itraconazole and topical ketoconazole.
June 2026 in “Journal of Cosmetic Dermatology” This review highlights that combination pharmacotherapy for androgenetic alopecia may offer enhanced hair growth efficacy and reduced side effects through distinct mechanisms, allowing for personalized treatment regimens that improve patient compliance and therapeutic outcomes.
26 citations
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December 2020 in “Genes” This study found that a combination of insulin-like growth factor-1 and epidermal growth factor significantly promoted hair follicle growth and development in both cultured hair follicles and rabbits.
23 citations
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September 2019 in “Journal of The American Academy of Dermatology” In this retrospective analysis, combination therapy with tofacitinib and oral minoxidil led to significant scalp hair regrowth in patients with severe alopecia areata, with 67% achieving at least 75% regrowth, although the small sample size limits the findings.
January 2023 in “Applied sciences” This study found that co-administering sasam-Kyeongokgo with gefitinib enhanced gefitinib's anti-tumor activity and exhibited favorable anti-cachexia effects in mice with non-small-cell lung cancer.
July 2022 in “Journal of Investigative Dermatology” This study analyzed randomized trials on low-level light therapy combined with minoxidil for androgenetic alopecia, reporting either superior or equivalent hair regrowth compared to minoxidil alone, with initial improvements tapering over time.
5 citations
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May 2025 in “Journal of the American Academy of Dermatology” 68 citations
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January 2012 in “Lasers in surgery and medicine” This study found that combining microdermabrasion, a topical regimen, and low-fluence QS Nd:YAG laser treatment effectively cleared melasma in women, with 81% of participants achieving over 75% clearance and minimal side effects.
18 citations
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July 2015 in “Journal of cosmetic dermatology” This study observed that combining hair dyeing with sodium hydroxide relaxers drastically increased protein loss in Caucasian virgin dark brown hair, while ammonium thioglycolate or guanidine hydroxide relaxers caused less damage.
8 citations
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January 2008 in “Annals of Dermatology” This study concluded that combining systemic cyclosporine A with low-dose corticosteroids effectively treats severe alopecia areata while maintaining safe cyclosporine A levels in the blood.
1 citations
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May 2024 in “Cureus” In this case study, the combination therapy of isotretinoin and rifampicin was reported to effectively improve symptoms in a 58-year-old female patient with folliculitis decalvans, suggesting this approach may warrant further investigation for treating this challenging condition.
April 2026 in “Brazilian Journal of Hair Health” In this case report, a 36-year-old male with androgenetic alopecia showed clinically visible improvement in hair density after three monthly sessions of microneedling combined with exosome application, although the authors note that further studies are needed to verify these findings.
59 citations
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May 1995 in “Journal of the American Academy of Dermatology” 64 citations
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January 1985 in “Clinical endocrinology” In this study, treatment with the oral contraceptive containing 30 μg ethinyl oestradiol and 150 μg desogestrel significantly reduced androgen-dependent hair growth in hirsute women over one year.
5 citations
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December 2020 in “Journal of The American Academy of Dermatology” This study observed objective improvement in androgenetic alopecia in 5 out of 6 adolescent girls treated with 2.5 mg oral minoxidil and spironolactone, and reported no adverse effects.
5 citations
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May 2017 in “Journal of dermatological science” This study reviewed the genetic and phenotypic aspects of Olmsted syndrome, highlighting pathogenic mutations in TRPV3 and MBTPS2 genes and their association with specific skin manifestations like symmetrical keratoderma and hyperkeratotic plaques.
1 citations
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November 2020 in “Dermatologic Surgery” Using combined hair restoration methods can effectively treat severe scalp wrinkling.
1 citations
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January 2022 in “Italian journal of dermatology and venereology” This study found that a topical treatment combining arginine and zinc significantly reduced hair loss and increased anagen hair percentage in patients with androgenetic alopecia and telogen effluvium, suggesting it might be a promising alternative to finasteride.
January 2025 in “Journal of the American Academy of Dermatology” Combining oral minoxidil and bicalutamide may help improve hair growth in adolescent girls.
The study found that the combined administration of regulatory T cells and rapamycin improved outcomes in an experimental model of chronic graft-versus-host disease.
June 2026 in “International Journal of Drug Delivery Technology” This study developed a Hyaluronic acid-Carbopol liposomal gel co-loaded with Adapalene and Clindamycin Phosphate, optimized to improve skin penetration and anti-acne efficacy, showing enhanced drug delivery, superior clinical effectiveness, and excellent skin tolerability compared to commercial formulations.