Efficacy of Platelet-Rich Plasma Combination Treatments in Dermatology: A Systematic Review

April 2023 in “ Journal of Investigative Dermatology ”

Simonetta I Gaumond, R. Abdin, M. Kaiser, E. Potter, J.J. Jimenez

platelet-rich plasma PRP androgenetic alopecia microneedling minoxidil acne scarring fractional carbon dioxide laser cutaneous rejuvenation hyaluronic acid fractional laser therapies Rogaine CO2 laser HA

TLDR Combining platelet-rich plasma with other treatments improves hair growth, acne scars, and skin rejuvenation.

The systematic review analyzed randomized control studies from 2012 to 2022 on the use of platelet-rich plasma (PRP) in combination with other treatments for androgenetic alopecia, acne scarring, and cutaneous rejuvenation. PRP, an autologous preparation of plasma with high concentrations of human platelets, promotes cell differentiation, proliferation, wound healing, and tissue remodeling. Five studies showed increased efficacy when PRP was combined with microneedling or minoxidil for treating androgenetic alopecia. Out of twelve studies on acne scarring, ten found that combining PRP with microneedling or fractional carbon dioxide laser led to significant clinical improvement and fewer side effects. For cutaneous rejuvenation, five out of seven studies found that combining PRP with microneedling, hyaluronic acid, or fractional laser therapies was more effective than using PRP alone. However, the review noted that more research is needed with standardized PRP preparation and experimental procedures, and that small sample sizes and insufficient patient follow-up times were limitations in the existing studies.

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research Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma for Treating Androgenic Alopecia

24 citations, November 2017 in “Aesthetic Plastic Surgery”

All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.