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Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Some types of extracellular matrix can change how human skin cells grow but don't affect their basic functions.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

The engineered skin substitute helped grow skin with hair on mice.

The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.

Future research should focus on making bioengineered skin that completely restores all skin functions.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Metformin helps improve skin regeneration by increasing the growth of skin stem cells.

The combined treatments were highly effective for improving atrophic acne scars.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Artificial skin is improving wound healing and shows potential for treating different types of wounds.

Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.

LED light therapy at 863 nm wavelength can slow down skin tumor growth and reduce inflammation in mice.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Activating Notch signaling can kill basal cell carcinoma cells.

Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.

Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.

Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Patients with rapidly progressive alopecia areata often have a better outlook and shorter disease duration, with regrown fine hairs and no past alopecia being positive signs.

Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.

New insights into cell communication in psoriasis suggest innovative drug treatments.

Inositol and arginine solutions improve hair follicle health and turnover.