10 citations
,
November 2009 in “Pigment cell & melanoma research” This study by Pérez-Oliva et al. explored how Mahogunin Ring Finger-1 (MGRN1) affects melanocortin-1 receptor (MC1R) signaling, suggesting that MGRN1 competitively inhibits Gαs binding to MC1R, influencing pigment production.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this review, researchers examined Tridax procumbens for its pharmacological and phytochemical potential, highlighting its diverse medicinal benefits, low toxicity, and the presence of bioactive compounds, positioning it as a promising candidate for developing safe and affordable plant-based therapeutics.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review of Tridax procumbens highlights its pharmacological and phytochemical potential, noting the presence of biologically active compounds and suggesting its value as a basis for developing new plant-based therapeutics due to its diverse medicinal properties and low toxicity.
October 2024 in “Rapid Communications in Mass Spectrometry” This study suggests that the shoulder guard hair of captive sika deer is effective for hair analysis, providing insights into growth patterns and isotopic changes that could aid future research on wild deer using hair samples.
November 2022 in “Brazilian journal of veterinary pathology” This case report describes a 1-year-old Yorkshire terrier presented with persistent alopecia and seborrhea in dark-haired areas, with no signs of hair regrowth despite treatment for folliculitis and seborrhea.
March 2021 in “Research Society and Development” This case study described a Staffordshire Bull Terrier diagnosed with alopecia by color dilution, characterized by gradual hair loss and confirmed through clinical examination and histopathology.
January 2005 in “Journal of Zhejiang University(Sciences Edition)” This study observed that Yuyi hairless mice develop alopecia shortly after birth, with the skin eventually thickening and forming folds, and hair failing to regrow as they age.
23 citations
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January 2016 in “Theranostics” In this animal study, ultrasound combined with a new microbubble formulation of minoxidil increased hair growth rates and improved follicle characteristics more effectively than minoxidil alone.
21 citations
,
November 2011 in “Veterinary Pathology” This study evaluated skin and hair color variations in different mouse strains, highlighting the association between hair cycle stages and skin pigmentation to better understand these features and their implications.
10 citations
,
July 2000 in “PubMed” This case report suggests that increased dietary calcium from alfalfa may have contributed to zinc deficiency in two adult female goats by blocking zinc absorption.
7 citations
,
September 2006 in “Molecular Carcinogenesis” This study observed that K5Cre +/+ transgenic mice develop a distinct phenotype characterized by wavy hair, curly whiskers, and an increased rate of papilloma malignant transformation.
October 2025 in “International Journal of Advanced Multidisciplinary Research and Studies” This study found that hairless dog breeds have adapted to maintain normal body and core temperatures through structural changes like a thicker epidermis and the role of melanin in thermoregulation, with genetic mechanisms involving the FOXI3 gene governing hairlessness.
January 2014 in “Spectrum Research Repository (Concordia University)” This study found that folic acid-conjugated magnetic nanoparticles loaded with doxorubicin significantly reduced cell proliferation in HeLa cells, although they were not effective against doxorubicin-resistant HeLa cells.
522 citations
,
January 2001 in “Cancer investigation” This review describes the unique pharmacological profile and clinical applications of pegylated liposomal doxorubicin, emphasizing its role in Kaposi's sarcoma and recurrent ovarian cancer, but reports no new clinical results.
231 citations
,
July 2008 in “Nutrition reviews” This review discusses environmental epigenomics and its potential impact on gene regulation and phenotypic outcomes, using the Avy mouse model to illustrate nutritional and environmental effects on the fetal epigenome without presenting new findings.
107 citations
,
June 1997 in “PubMed” In this study, disrupting the epidermal growth factor receptor in mice led to abnormal hair and skin development, characterized by disorganized hair follicles and systemic disease, providing a model for understanding EGFR's role in skin biology.
31 citations
,
November 1965 in “Journal of Mammalogy” This study found that in mink, the pituitary gland is essential for normal seasonal pelage cycles, and manipulating hormone levels can affect hair growth and type.
29 citations
,
February 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study, researchers observed that the absence of a functional vitamin D receptor in mice leads to impaired hair follicle regeneration due to defects in keratinocyte stem cells, resulting in alopecia.
27 citations
,
July 2018 in “Experimental dermatology” This study found that autophagy plays a role in sebaceous gland function and sebum composition control in mice lacking the Atg7 gene in keratinocytes.
26 citations
,
December 2021 in “Regenerative Biomaterials” This study found that an injectable ceria-based nanocomposite hydrogel improved wound healing and epithelium regeneration, including hair follicle and adipocyte tissue formation, in full-thickness skin wound models.
22 citations
,
September 2022 in “Materials & Design” This study found that bioactive glass-based camouflage composite particles enhanced the coagulation effects in bleeding models by forming a fibrin network and activating coagulation pathways, suggesting potential use as an emergency hemostasis biomaterial.
20 citations
,
July 2005 in “Experimental dermatology” This study found that the fuzzy mutation in mice is linked to both structural hair defects and accelerated hair follicle cycling, influencing the regulation of hair cycle phases such as catagen and anagen.
15 citations
,
May 1986 in “Journal of the American Veterinary Medical Association” In this study, a dog with alopecia and a Sertoli cell tumor showed hyperprogesteronemia, and its hair regrew after castration, with progesterone levels reducing toward normal.
15 citations
,
September 1970 in “Journal of Animal Science” This study investigated how dietary copper affects hair pigmentation and mineral concentrations in calves, reporting on copper's influence but not providing definitive results.
13 citations
,
January 2014 in “Journal of Veterinary Internal Medicine” This case study reports an instance of adult-onset primary hypothyroidism with goiter in a cat, suggesting potential causes such as dietary iodine imbalance, chronic exposure to thyrotoxic substances, or a congenital form with late manifestation.
12 citations
,
July 1958 in “Journal of Endocrinology” In this animal study, cortisone injections inhibited hair regrowth in rats and rabbits, while bilateral adrenalectomy did not significantly affect the hair regrowth cycle.
12 citations
,
January 2003 in “PubMed” This study reported that Diane-35 treatment over 6-9 months reduced hair loss, hair thinning, and seborrhoea in women with androgenetic alopecia.
11 citations
,
February 1989 in “Journal of veterinary medicine. Series A” This study observed that congenital hypotrichosis in crossbred cattle is linked to short, curly, dilute-color hair, potentially due to color dilution mutants in European breeds.
10 citations
,
December 2023 in “International Journal of Nanomedicine” This study reviewed the challenges of delivering nucleic acids for gene therapy, highlighting the limitations of non-viral vehicles and exploring bioinspired strategies using cell membrane camouflage for improved delivery efficacy.
10 citations
,
November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced laser particles as a new imaging probe capable of real-time tracking of thousands of individual cells in 3D tumor models, suggesting potential for advanced single-cell analyses.