54 citations
,
January 2016 in “Cell reports” This study found that different epidermal stem cell populations contribute to the formation of various skin tumors and new hair follicles following β-catenin activation in the adult epidermis.
54 citations
,
May 2021 in “Chemical Engineering Journal” This study found that a novel hybrid bilayer scaffold system enhanced wound healing in an in-vivo model by promoting cell viability, migration, and preventing infection, showing potential as an advanced dressing for cutaneous wounds.
54 citations
,
September 2012 in “Acta ophthalmologica” This review highlights that various targeted cancer therapies are associated with specific ocular side-effects, emphasizing the importance of awareness among ophthalmologists for timely diagnosis and management.
54 citations
,
February 2010 in “British Journal of Dermatology” This case report describes a patient with complete androgen insensitivity syndrome experiencing female pattern hair loss, suggesting that factors beyond direct androgen action may contribute to this condition in women.
54 citations
,
August 2009 in “Dermatologic Surgery” This review outlines the steps of contemporary hair transplantation surgery, including the roles of medications and nonsurgical options, but it reports no new clinical findings.
53 citations
,
August 2014 in “Cochrane library” This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.
53 citations
,
January 2012 in “Developmental Biology” EGFR signaling is essential for ear cell regeneration in both birds and mammals.
53 citations
,
July 2016 in “Cosmetics” This study reviews the biology and cosmetic treatment of hair, emphasizing future advancements in safer, more effective procedures to meet consumer needs for hair care.
53 citations
,
August 2015 in “The Italian Journal of Pediatrics/Italian journal of pediatrics” This review discusses congenital generalized hypertrichosis, focusing on its association with complex malformation syndromes, but it presents no new research findings.
53 citations
,
March 2006 in “Biopolymers” This study suggests that increased amounts of less stable disulfide conformers in hair shafts may be linked to the brittleness observed in trichothiodystrophy.
53 citations
,
November 1997 in “Journal of Forensic Sciences” This study found that codeine incorporation in guinea pig hair varied with pigmentation and was highest in black hair, suggesting the role of eumelanins in drug binding.
53 citations
,
May 1988 in “Journal of Molecular Evolution”
53 citations
,
June 1982 in “The BMJ” Cooling the scalp below 22°C before and during chemotherapy can help prevent hair loss.
53 citations
,
January 1953 in “The journal of nutrition/The Journal of nutrition” This study found that newborn mice deprived of colostrum developed disorders linked to zinc deficiency, and administering inorganic zinc prevented these conditions.
52 citations
,
March 2022 in “Biology of Sex Differences” This review examines biological reasons for sex-based differences in COVID-19 outcomes, noting that females exhibit stronger immune responses, potentially explaining lower severity and mortality compared to males.
52 citations
,
January 2021 in “Journal of Thoracic Oncology” Effective vaccines and treatments are crucial for long-term COVID-19 control.
52 citations
,
May 2013 in “Supportive Care in Cancer” Scalp cooling significantly reduces hair loss in chemotherapy patients.
52 citations
,
April 2008 in “Therapeutics and clinical risk management” This review covers the use of combined oral contraceptives, particularly drospirenone, for managing polycystic ovary syndrome and discusses related metabolic controversies without reporting new clinical results.
52 citations
,
January 2023 in “Toxins” This narrative review discusses expert consensus on the optimal use of botulinum toxin injections for cosmetic applications in facial and oral-maxillofacial areas across Asian and Caucasian populations, highlighting injection techniques, effective doses, historical context, and potential complications.
52 citations
,
January 2016 in “Brazilian Journal of Medical and Biological Research” In this study, patients with generalized vitiligo treated with a combination of oral compound glycyrrhizin and UVB light showed the most effective repigmentation and disease stabilization compared to other treatment groups.
52 citations
,
April 2002 in “Brain Research” This study found that in rats, finasteride significantly reduced allopregnanolone in the cortex and increased both the rise and duration of dopamine levels in the prefrontal cortex in response to stress and anxiogenic stimuli.
52 citations
,
September 1996 in “Obstetrics & Gynecology” This study found that compliance rates for oral contraceptives are low and similar to those for other medical treatments, indicating a need for alternatives that require less daily adherence.
52 citations
,
August 1993 in “Clinical endocrinology” This study found that intravenous high dose calcium infusions followed by high dose oral calcium effectively treated vitamin D dependent rickets type II, leading to complete biochemical and radiological healing and improved growth in two patients.
52 citations
,
December 1984 in “Journal of the American Geriatrics Society” This study found that serum and hair mineral concentrations, including copper and zinc, showed no differences between Alzheimer's patients and their healthy spouses, suggesting no diagnostic utility for Alzheimer's disease.
51 citations
,
August 2015 in “Cochrane library” This systematic review reports that there is currently no evidence supporting methotrexate for maintaining remission in ulcerative colitis; further large-scale trials are needed to assess its efficacy and safety.
51 citations
,
October 2012 in “International Journal of Immunopathology and Pharmacology” In this study, 68% of patients treated with finasteride showed improved hair growth in male androgenetic alopecia, compared to 38% with Serenoa repens, indicating finasteride's superior efficacy.
51 citations
,
November 2005 in “Journal of Medical Primatology” This study observed that hair loss in captive rhesus macaques varies with season, sex, and housing conditions, and is significantly correlated with HPA axis activity as indicated by faecal cortisol metabolites.
51 citations
,
March 1986 in “Acta Dermato Venereologica” This study found no differences in trace element concentrations between Finnish alopecia patients and the normal population, but noted significant serum copper variation among different alopecia subtypes.
51 citations
,
July 2023 in “American Journal of Clinical Dermatology”
51 citations
,
November 2020 in “Journal of the European Academy of Dermatology and Venereology” This article discusses SARS-CoV-2-induced telogen effluvium in a multicentric study and reports no new clinical results.