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In this study, researchers found that cepharanthine significantly inhibited the growth of non-small cell lung cancer cells by inducing apoptosis through ROS generation and altering multiple signaling pathways, suggesting potential as a novel lung cancer treatment.

This source reports that a comprehensive review of LSS gene variant phenotypes enhances understanding of congenital hypotrichosis 14 and could guide more precise genetic counseling and future research into disease mechanisms and potential therapies.

In this study, 12-Chloracetyl-PPD showed anti-cancer activity by inhibiting cancer cell viability and inducing apoptosis through reactive oxygen species production without harming normal cells.

This case study documents the first reported instance of bullous lichen planus/systemic lupus erythematosus overlap syndrome with initial hair loss, which improved with treatment including glucocorticoids and immunosuppressive drugs.

In this observational study, the Liposome-Paclitaxel plus Carboplatin regimen showed better short-term efficacy and comparable long-term outcomes for serous ovarian cancer compared to other regimens.

This study found that NB-002 demonstrated clear antifungal activity and clinically significant nail clearing in subjects with distal subungual onychomycosis and ≤50% nail involvement, compared to a vehicle treatment.

In a rat model of chemotherapy-induced alopecia, this study found that low-level laser treatment significantly accelerated hair regrowth without affecting the efficacy of chemotherapy.

This study presented cases of severe and permanent nail changes resembling lichen planus in patients with chilblain lupus erythematosus, suggesting a unique pattern related to cold exposure rather than typical histopathology findings.

This study reports that using machine learning models, particularly XGBoost and Random Forest, can accurately predict PCOS phenotypes based on non-invasive data, with cycle length as the most significant predictor.

This review discusses the etiology of moth-eaten alopecia patterns in lichen planopilaris and emphasizes the importance of early diagnosis and treatment to prevent permanent scarring, offering no new empirical findings.

This study found that while epidermal PLCγ1 is not necessary for keratinocyte differentiation in interfollicular epidermis, it is crucial for normal hair and sebaceous gland formation in mice.

Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.

In this study, the gene SlPHL1 was identified as a transcription factor in tomatoes that enhances phosphate starvation responses by upregulating specific genes.

This study observed that in a series of 28 patients with different types of alopecia, specific trichoscopic markers like exclamation-mark hairs and yellow dots helped distinguish alopecia areata from conditions like lichen planopilaris and discoid lupus erythematosus, which showed follicular ostia loss and white scarring.

This report details a case of a 3-year-old child with Clouston syndrome, a rare inherited disorder affecting nails, skin, and hair, highlighting the need for supportive management due to the absence of treatment options.

CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.

This case report describes a 2-year-old boy with uncombable hair syndrome-like hair changes that resolved spontaneously after 9 months, with genetic analysis revealing a PLCD1 gene variant.

ChatGPT is preferred for creating dermatology patient handouts, but all models can be useful with oversight.

This study found that melatonin-mediated lncRNA018392 accelerated cell proliferation and inhibited apoptosis in cashmere goat skin fibroblasts by upregulating the expression of the nearby gene CSF1R.

This study identified a 14,883 bp genomic deletion affecting the Plcd1 and Vill genes as likely responsible for the abnormal phenotype observed in snthr-1Bao mice.

This study identified a new variety of central centrifugal cicatricial alopecia that includes patchy hair loss on the lateral and posterior scalp in African-American women, which could be misdiagnosed as traction alopecia without dermatoscopy and pathology.

This study reports the first known case of multiple type nevus lipomatosus cutaneous superficialis in a 10-month-old girl, with the unique feature of perifollicular fibrosis.

This study found that their newly developed ADRL framework significantly improved the accuracy of scalp tissue layer segmentation in HR-MR images compared to existing methods.

This study described a case where lupus erythematosus panniculitis preceded the diagnosis of systemic lupus erythematosus, highlighting the need for regular follow-ups in LEP patients for potential SLE development.

This study found that Cornu cervi pantotrichum pharmacopuncture solution significantly promoted hair growth in mice by enhancing hair follicular cell proliferation and up-regulating FGF-7 expression.

Dermoscopy helped diagnose discoid lupus erythematosus in two patients without needing skin biopsies.

This study found that patients with oral lichen planus and oral lichenoid reactions have higher levels of serum cholesterol and LDL-C than healthy individuals, suggesting a potential elevated risk for cardiovascular disease.

In this study, a mouse model of scarring alopecia demonstrated significantly reduced CD200R expression in affected skin, which may contribute to immune attacks on hair follicles.

This case report suggests that identifying hyperpigmentation on the upper eyelid with specific dermoscopy patterns could help diagnose facial lichen planus pigmentosus without needing a facial biopsy.

This study demonstrated that de novo designed bifunctional proteins can target and degrade BCL-xL, leading to cell apoptosis, suggesting a new approach to targeted protein degradation therapy.