81 citations,
July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
13 citations,
September 2008 in “Experimental and Clinical Endocrinology & Diabetes” Young women with PCOS without additional risk factors may have normal heart function.
4 citations,
January 2015 in “Journal of clinical & experimental dermatology research” PRP injections may slightly improve hair density and count for male hair loss, but more research is needed.
August 2024 in “International Journal of Basic & Clinical Pharmacology” Secretome-based therapies could improve hair growth better than current treatments.
52 citations,
January 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.
28 citations,
October 1998 in “Baillière's clinical endocrinology and metabolism” Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
22 citations,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
17 citations,
January 2014 in “Journal of Clinical and Diagnostic Research” Patients with oral lichen planus or oral lichenoid reactions had worse cholesterol levels and a higher risk of obesity compared to healthy individuals.
9 citations,
February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.
October 2018 in “Journal of Clinical Research in Pediatric Endocrinology” Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.
3 citations,
November 2021 in “Clinical, Cosmetic and Investigational Dermatology” Autologous cellular micrografts improve hair density and thickness in the short term for androgenetic alopecia.
1 citations,
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” A condition with certain scalp changes may come before acne keloidalis nuchae and other similar hair loss disorders.
April 2023 in “Clinical Chemistry and Laboratory Medicine” The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
May 2019 in “Journal of clinical oncology” Radiation therapy with chemotherapy can cause severe, long-lasting hair loss.
19 citations,
February 2021 in “Journal of Clinical Investigation” More research is needed on the health effects of hormone therapy for transgender and nonbinary people.
11 citations,
April 2014 in “Journal of Clinical Virology” Older age, pre-existing skin conditions, cirrhosis, and pegylated interferon use increase the risk of skin issues during hepatitis C treatment.
6 citations,
November 2019 in “The application of clinical genetics” The study found that a specific genetic variation in the TNFα gene is significantly linked to Alopecia Areata in the Jordanian Arab population.
224 citations,
February 2013 in “The Journal of clinical investigation/The journal of clinical investigation” ERG increases SOX9, promoting prostate cancer growth and invasion.
26 citations,
June 2020 in “The Journal of Allergy and Clinical Immunology In Practice” A patient developed a severe skin reaction and died after taking hydroxychloroquine for COVID-19.
12 citations,
January 2018 in “Journal of Clinical Laboratory Analysis” Certain IL-18 gene variations may increase the risk of alopecia areata.
9 citations,
July 2022 in “Journal of Clinical Oncology” Oral paclitaxel plus encequidar improved tumor response and caused less neuropathy but more serious infections than intravenous paclitaxel.
6 citations,
September 2022 in “Journal of Clinical Medicine” The treatment might help COVID-19 related hair loss, but more research is needed.
4 citations,
November 2021 in “Journal of Clinical Medicine” Higher levels of CCL7 are linked to more severe hair loss in alopecia areata patients.
January 2023 in “International journal of clinical medicine” Women with PCOS and hair loss have lower levels of the protein gelsolin in their blood.
November 2022 in “The Journal of Clinical Endocrinology and Metabolism” Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.
61 citations,
April 2012 in “British Journal of Dermatology” Caucasian women's hair appears thickest in their 20s, with perceived thinning after mid-30s due to both decreasing density and diameter.
18 citations,
July 2016 in “Medicine” Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.
24 citations,
November 2013 in “British Journal of Dermatology” Chemotherapy causes hair loss starting soon after treatment begins and recovers about 3 months after ending, while tamoxifen does not significantly affect hair growth.
6 citations,
March 2020 in “Journal of International Medical Research” Early hair loss common in Chinese males, linked to family history and smoking; early treatment advised.
1 citations,
September 2013 in “Fertility and Sterility” Finasteride may improve sperm count in subfertile men with low sperm count.