297 citations
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January 2002 in “Development” In this study, repressing β-catenin/Lef1 signalling in mouse epidermis led to progressive hair loss, dermal cysts, and spontaneous skin tumors with sebaceous differentiation, indicating altered keratinocyte differentiation and potential tumourigenic processes.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)”
1 citations
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January 2016 in “Hair therapy & transplantation” In this study, male participants with early androgenetic alopecia experienced a significant increase in hair growth rate after applying topical lipoid cepharanthine lotion for six months.
44 citations
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April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
August 2016 in “Journal of Investigative Dermatology” This study reported improvement in hair loss lesions in C3H/HeJ mice with alopecia areata following treatment with the CCR5 inhibitor maraviroc, alongside reduced infiltration of specific T cells in the lesions.
January 2011 in “한국미생물·생명공학회지” In this study, Pleuropterus cilinervis extracts and animal milk fermented with Lactobacillus rhamnosus were found to enhance hair re-growth in mice more than the positive control treatment.
December 2012 in “Journal of undergraduate research in Alberta” This study suggests that primary cilia may enhance the proliferation of skin-derived precursors when combined with lithium chloride and platelet-derived growth factor, potentially targeting them for stem cell-based therapies.
This study concluded that removing alopecia and mucous membrane components from the CLASI-A score limits the ability to capture crucial clinical information about cutaneous lupus erythematosus activity, recommending their retention.
106 citations
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February 2014 in “eLife” This study concluded that terminal Schwann cells are essential for the maintenance and regeneration of mechanosensory lanceolate complexes at hair follicles in adult mice.
December 2013 in “Pump Industry Analyst” This study found that using particle-based antigen delivery in combination with cyanoacrylate skin surface stripping is an effective needle-free method for targeting HIV-1 p24 protein to skin cells, enhancing transcutaneous vaccination potential.
46 citations
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November 2019 in “Journal of Integrative Plant Biology” This study found that calmodulin 7 (CaM7) inhibits the calcium channel CNGC14 in root hairs, affecting their polar growth by controlling calcium signaling.
21 citations
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May 2018 in “Journal of Cosmetic Dermatology” This study found that costunolide promotes hair growth in both lab-cultured human hair follicle cells and in live mice by modulating growth factor pathways.
10 citations
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November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced laser particles as a new imaging probe capable of real-time tracking of thousands of individual cells in 3D tumor models, suggesting potential for advanced single-cell analyses.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that a mathematical model predicts signaling heterogeneity in epithelial outer root sheath cells is necessary for hair follicles to maintain size and grow long hair fibers, supported by molecular experiments.
5 citations
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July 2013 in “Our Dermatology Online” This study found that lichen planopilaris was the most common variant of cicatricial alopecia among patients, with perifollicular fibrosis being a prevalent histopathological feature.
October 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study discovered a novel mechanism by which germ stem cells exit their niche in C. elegans, involving thin membranous protrusions from adjacent somatic gonad cells.
October 2014 in “Microscopy” This study found that using ionic liquid for specimen preparation allowed for observation of dermal papilla cells and their cilia in near-living conditions, reducing damage typically caused by conventional preparation methods.
January 2025 in “SSRN Electronic Journal” 13 citations
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January 2006 in “PubMed” This article describes various causes and histological characteristics of cicatricial alopecia and emphasizes the need for further research into its causes and treatment options but reports no new findings.
April 2023 in “CRC Press eBooks” This research highlights the key interactions of hair cosmeceuticals, focusing on their effects on the hair fiber surface, cuticle, and cortex, which are crucial for protection and mechanical strength, particularly in damaged hair.
January 2026 in “Dermatology Online Journal” This case report highlights that CCCA can present with multifocal patchy hair loss in younger men of African descent, suggesting the need for careful evaluation when diagnosing atypical alopecia patterns.
6 citations
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February 2023 in “Genes” This study found that overexpression of the CUX1 protein promotes proliferation of Hu sheep dermal papilla cells and affects key genes in the Wnt/β-catenin signaling pathway.
54 citations
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January 2016 in “Cell reports” This study found that different epidermal stem cell populations contribute to the formation of various skin tumors and new hair follicles following β-catenin activation in the adult epidermis.
5 citations
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January 2024 in “The International Journal of Developmental Biology” This article reviews the diversity of lymphatic endothelial cells, related gene targeting tools, and protocols in mouse models but presents no new experimental findings.
5 citations
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September 2022 in “Antioxidants” This study found that the clionasterol-rich hexane fraction of Caulerpa racemosa may protect against particulate matter-induced skin damage by reducing oxidative stress and mitochondrial-mediated apoptosis in human keratinocytes and zebrafish.
February 2023 in “Molecules” In this study, N. ottonis cactus cell extract applied to mice promoted hair growth and increased the number of hair follicles, suggesting its potential as a hair-growth-promoting agent.
1 citations
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May 2024 in “Skin Appendage Disorders” This study describes trichoscopic findings in 11 dark-skinned women with central centrifugal cicatricial alopecia and highlights the potential of trichoscopy for early diagnosis and treatment.
3 citations
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August 2019 in “Journal of Cancer Research and Therapeutics” This case report describes an unusual combination of hypertrichosis, androgenic alopecia, and trichomegaly in a patient with metastatic colon adenocarcinoma treated with cetuximab, with no adrenal or hormonal abnormalities detected.
158 citations
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December 2002 in “Development” In this study, Msx2-deficient mice showed progressive hair loss due to shortened anagen phase and prolonged catagen and telogen phases, resulting in cyclic alopecia with structurally abnormal hair shafts.
9 citations
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July 2020 in “JAMA dermatology” This study explored dermatoscopic and histopathologic findings of central centrifugal cicatricial alopecia beyond the vertex scalp, suggesting that dermatoscopy might serve as a less invasive diagnostic tool for subclinical disease.