2 citations
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May 2021 in “Journal of pharmaceutical and biomedical analysis” This study utilized a UHPLC-HRMS method to identify eight active pharmaceutical ingredients, such as ketoconazole and minoxidil, in 26 out of 100 analyzed cosmetic products.
67 citations
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December 1990 in “The journal of cell biology/The Journal of cell biology” This study identified two evolutionarily conserved ultra-high-sulfur keratin proteins in human and sheep hair follicles, which are specifically expressed in the hair cuticle during the late stages of fiber development.
52 citations
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September 2021 in “Kidney International” In this report, a 23-year-old woman developed nephrotic syndrome and was diagnosed with lupus nephritis after receiving the first dose of the AstraZeneca COVID-19 vaccine, but causation is not established.
9 citations
,
December 2014 in “British Journal of Dermatology” This letter discusses potential hair loss effects of Hedgehog inhibitors but presents no new clinical findings, urging further exploration of this possible class effect.
8 citations
,
October 2016 in “Experimental dermatology” This paper proposes that the induction of HF-specific neo-antigens by peripheral CD8+ T cells may maintain self-tolerance but could also lead to immunopathology in conditions like alopecia areata.
July 2026 in “Journal of Ayurveda and Integrated Medical Sciences” This study reported that a 30-year-old female patient with hypothyroidism experienced significant health improvements, including weight loss and better lipid profiles, after undergoing Ayurvedic Panchakarma therapies, oral medications, and a tailored diet and yoga plan over one week.
Topical corticosteroids are effective for skin conditions but can have side effects.
January 2006 in “The journal of clinical and aesthetic dermatology” This study found high patient satisfaction and quality of life in women with androgenetic alopecia using 5% minoxidil, although hair loss still influenced their social life and daily habits.
February 2025 in “Animals” In this review, researchers examined the molecular diversity and expression patterns of major skin appendage proteins, like keratins and EDC proteins, in tetrapods, highlighting recent findings in reptiles and birds and identifying knowledge gaps for future research.
355 citations
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January 2017 in “Journal of the American Academy of Dermatology” This review reports no new results and highlights existing research suggesting JAK inhibitors may be effective in treating inflammatory skin conditions like alopecia areata, atopic dermatitis, psoriasis, and vitiligo.
56 citations
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December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
38 citations
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October 2005 in “Expert opinion on therapeutic patents” This review discusses nonsteroidal selective androgen receptor modulators and their potential therapeutic applications but reports no new clinical findings.
28 citations
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September 2000 in “Journal of Medicinal Chemistry” This study identified novel compounds as selective inhibitors of the type 1 isoenzyme of 5α-reductase, displaying promising potential for treating DHT-dependent disorders such as acne and androgenic alopecia.
17 citations
,
December 2015 in “Bioorganic & Medicinal Chemistry” 3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.
2 citations
,
November 2015 in “Journal of Investigative Dermatology” This study found that RANKL signaling enhances CD8+ T cell-mediated anti-viral immunity during herpes simplex virus infection by preventing apoptosis of Langerhans cells, suggesting potential therapeutic applications.
May 2026 in “International Journal of Drug Delivery Technology” This study reports that using machine learning models, particularly XGBoost and Random Forest, can accurately predict PCOS phenotypes based on non-invasive data, with cycle length as the most significant predictor.
In this study, a deep learning model using an optimized VGG19 architecture achieved a high classification accuracy of 98.64% for detecting ten hair disease classes from a balanced dataset, indicating its potential for reliable use in mobile diagnostics for clinical and remote applications.
July 2024 in “Journal of Investigative Dermatology” ITK inhibitors may effectively treat alopecia areata.
This study found significant cephalometric changes in patients with skeletal Class III malocclusion treated with rapid maxillary expansion and reverse traction, demonstrating maxilla advancement and improved facial convexity.
3 citations
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July 2023 in “Biomolecules” This study reports that some human cell surface HLA-I molecules (including HLA-B27) can appear without their usual peptide component, potentially altering immune interactions, influencing arthritis development in specific mice models, and exhibiting upregulation in certain cancer cells.
1 citations
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January 2024 in “Pharmaceuticals” The researchers reported that dPGS-PCL as a carrier improved the penetration of tofacitinib in an ex-vivo human skin model compared to free tofacitinib, but did not show significant differences in inhibiting IL-6 and IL-8 during short incubation.
This study developed a high-performance deep learning model using the Inception-ResNet v2 architecture to classify 10 hair disease classes, achieving an accuracy of 94.7% and balanced precision, recall, and F1-scores of 0.94, suggesting reliability for automated dermatology diagnostics.
January 2020 in “Sumatera Medical Journal” In this study, family history was identified as the most significant risk factor for premature hair graying among medical students at the University of Sumatera Utara.
12 citations
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December 2013 in “The Journal of Urology” Men's age, urinary symptoms, and heart health risks create different types of erectile dysfunction.
1 citations
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April 2025 in “Dermatology and Therapy” This study identified three patient groups based on the psychological and social impact of vitiligo, with the most affected group experiencing severe psychosocial burdens despite often having mild physician-reported disease severity.
1 citations
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September 2020 in “Medicina y Laboratorio” This review examines platelet-rich plasma therapy for musculoskeletal and soft tissue injuries and reports no firm evidence supporting its routine use due to poor study design and inconsistent results.
January 2018 in “Dermatology Online Journal” This review discusses current pharmacological proposals for treating alopecia areata, highlighting the need for individualized treatment plans due to limited clinical trial evidence and potential for spontaneous remission.
68 citations
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April 2014 in “Journal of Investigative Dermatology” This study identified a new S100 fused-type protein, scaffoldin, in reptiles and birds and suggests that SFTP-positive epithelia serve as scaffolds for the growth of various skin appendages, indicating a common evolutionary origin.
36 citations
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November 2019 in “Molecular biology and evolution” This study suggests that the keratins found in reptile and bird skin appendages evolved independently from mammalian hair keratins, highlighting convergent evolution in these species.
17 citations
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August 2014 in “The Anatomical Record” The researchers reported that scaffoldin, a protein identified in chicken embryos, likely plays a role in forming periderm granules and contributes to the soft cornification of embryonic epidermis.