research LncRNAs Regulate the Cyclic Growth and Development of Hair Follicles in Dorper Sheep
Certain long non-coding RNAs are important for controlling hair growth cycles in sheep.
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research Lenalidomide Augments Differentiation of Cultured Hair Follicle Derived Melanocyte Stem Cells Into Functional Melanocytes
Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.
research Exosomes for Regeneration, Rejuvenation, and Repair
Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
research Molecular Genetics of Androgen Insensitivity
Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.
research RNA Interference of NtNCED3 Reduces Drought Tolerance and Impairs Plant Growth Through Feedback Regulation of Isoprenoids in Nicotiana Tabacum
Silencing NtNCED3-2 gene in tobacco reduces drought tolerance and impairs growth.
research Dynamic Regulation of Retinoic Acid-Binding Proteins in Developing, Adult, and Neoplastic Skin Reveals Roles for β-Catenin and Notch Signaling
Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
research TOR Tour to Auxin
The plant hormone auxin activates the TOR pathway, affecting gene expression related to growth and cell size.
research Male Hair Loss – What Our Genes Reveal
Genetic research may lead to better ways to predict and treat male-pattern hair loss.
research Transcriptional Regulation of the Thymus Master Regulator Foxn1
Foxn1 gene regulation is crucial for thymus development but not for hair growth.
research Poly(rC) Binding Protein 2 Acts as a Negative Regulator of IRES-Mediated Translation of Hr mRNA
A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.
research Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity
Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research 17β-Estradiol Inhibits the Production of RANTES in Human Keratinocytes
17β-estradiol can reduce inflammation in the skin.
research Position Effect on FGF13 Associated with X-Linked Congenital Generalized Hypertrichosis
FGF13 gene changes cause excessive hair growth in a rare condition.
research Genetic Basis of Alopecia Areata
More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.
research Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis
P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
research The Genetic Architecture of Alopecia Areata
Genetic discoveries are leading to new treatments for alopecia areata.
research Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 NKG2D Lymphocytes in Alopecia Areata Patients
EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.
research Arabidopsis PCaP2 Functions as a Linker Between Abscisic Acid and Salicylic Acid Signals in Plant Water Deficit Tolerance
Arabidopsis PCaP2 helps plants survive drought by linking ABA and SA signals.
research Skipping of Exons by Premature Termination of Transcription and Alternative Splicing Within Intron-5 of the Sheep SCF Gene: A Novel Splice Variant
A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.
research Selection Signatures for Fiber Production in Commercial Species: A Review
Genomic research can help improve the quality and production of natural fibers in animals.
research Genome Wide Association Analysis of Root Hair Traits in Rice Reveals Novel Genomic Regions Controlling Epidermal Cell Differentiation
Scientists found new genetic areas that affect how rice root hairs grow and develop.
research Analysis of 72,469 UK Biobank Exomes Links Rare Variants to Male-Pattern Hair Loss
Rare genetic variants in five specific genes are linked to male-pattern hair loss but only account for a small part of the risk.
research miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network
miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.
research Synchronous Profiling and Analysis of mRNAs and ncRNAs in the Dermal Papilla Cells from Cashmere Goats
Non-coding RNAs help control hair growth in cashmere goats.
research Functional Mapping of the Mouse Hairless Gene Promoter Region
Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
research Oral Retinoids in Dermatology
Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research GDNF Promotes Hair Formation and Cutaneous Wound Healing by Targeting Bulge Stem Cells
GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
research The Pioneer Factor SOX9 Competes for Epigenetic Factors to Switch Stem Cell Fates
SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.