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In teens with Polycystic Ovary Syndrome and obesity, issues related to metabolism, skin, and mental health are common, and a clinic with various specialists can provide care for most of these problems.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

Melatonin may protect inner ear cells from damage by reducing cell death and oxidative stress, potentially treating sudden hearing loss.

Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.

Non-drug therapies show promise for hair regrowth but need more research.

Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Hair growth and development are controlled by specific signaling pathways.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.

Old hair follicles grew better when moved to a young environment.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Young women with nonclassic congenital adrenal hyperplasia may experience worse sexual function and mild depression compared to healthy women.

Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Men with more severe hair loss had a lower risk of schizophrenia, but hair loss and testosterone levels were not linked.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

DNA methylation changes are linked to hair growth cycles in goats.

Gut microbes significantly affect brain steroid levels.

The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Ephrins slow down skin and hair follicle cell growth.