Comparison of Alopecia Severity and Blood Level of Testosterone in Men Suffering Schizophrenia with Control Group

January 2013 in “ Advanced Biomedical Research ”

Gholamreza Kheirabadi, Ali Yazdani, Leila Golfam

alopecia testosterone androgenic alopecia Hamilton scale androgens antipsychotics hair loss male pattern baldness

TLDR Men with more severe hair loss had a lower risk of schizophrenia, but hair loss and testosterone levels were not linked.

In 2012, a study involving 98 men with schizophrenia and 95 without was conducted to investigate the relationship between testosterone levels, alopecia, and schizophrenia. The study found no significant difference in testosterone levels between the two groups, nor a significant relationship between alopecia severity and testosterone levels. However, it was discovered that if the severity of Androgenic Alopecia exceeded grade 2 on the Hamilton scale, the risk of schizophrenia decreased 8.62 times, suggesting that sensitivity to Androgens and Alopecia may play a protective role against schizophrenia. The study also found that testosterone levels in patients treated with certain antipsychotics were significantly lower than the control group, but there was no significant difference in alopecia rates. The pattern of alopecia could potentially be used as a predictor symptom for the likelihood of schizophrenia in at-risk individuals.

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Research cited in this study

3 / 3 results

research Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities

126 citations, January 2010 in “British Journal of Dermatology”

Baldness is more common in Chinese men than women, increasing with age, and is influenced by genetics.

research Validity of Self-Reported Male Balding Patterns in Epidemiological Studies

32 citations, December 2004 in “BMC Public Health”

Men can report their own balding patterns well enough for large health studies.

research Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex

666 citations, September 1977 in “British Journal of Dermatology”

Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.

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