research Melatonin Promotes Hair Regeneration by Modulating the Wnt/β-Catenin Signaling Pathway
Melatonin helps hair grow by activating a specific signaling pathway.
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research Efficacy and Safety of Topical Rosuvastatin and Melatonin vs. Placebo in Patients with Mild to Moderate Plaque Psoriasis: A Preliminary Randomized Double-Blinded Clinical Trial
Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
research In The Quest To Stymie Time, Will Laboratory Data Stand Up In Man?
Genetic manipulations that extend lifespan in mice may not work as effectively in humans.
research The Cascading Pathogenic Consequences of Sarcoptes Scabiei Infection That Manifest in Host Disease
Sarcoptes scabiei infection causes significant health and behavior changes in wombats.
research Care for Adolescents With Polycystic Ovary Syndrome: Development and Prescribing Patterns of a Multidisciplinary Clinic
In teens with Polycystic Ovary Syndrome and obesity, issues related to metabolism, skin, and mental health are common, and a clinic with various specialists can provide care for most of these problems.
research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
research Relation of 24-Hour Urinary Aldosterone Levels with Nondipper Blood Pressure Pattern in Normotensive Individuals
Higher aldosterone levels in urine are linked to a nondipper blood pressure pattern in healthy people.
research Testosterone Implants in Women: Pharmacological Dosing for a Physiologic Effect
Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
research Melatonin Alleviates Oxygen-Glucose Deprivation/Reperfusion-Induced Pyroptosis of HEI-OC1 Cells and Cochlear Hair Cells via MT-1,2/Nrf2/ROS/NLRP3 Pathway
Melatonin may protect inner ear cells from damage by reducing cell death and oxidative stress, potentially treating sudden hearing loss.
research Correlation Between High Hair Cortisol Level and Intracranial Aneurysm Rupture
High levels of cortisol in hair are linked to a greater risk of brain aneurysm rupture.
research Is It Getting in the Hair? Cortisol Concentrations in Native, Regrown, and Segmented Hairs of Cattle and Pigs After Repeated ACTH Administrations
Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.
research Evaluation of Coronary Sinus Strain in Patients with Dipper and Non-Dipper Hypertension
People with non-dipper hypertension have higher aldosterone levels, more strain on their heart's venous system, and increased risk of endothelial dysfunction.
research Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility
Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
research Effects of Melatonin Administration on Mental Health Parameters, Metabolic and Genetic Profiles in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
Melatonin improved mental health and metabolism in women with PCOS.
research Testosterone Therapy for Women with Low Sexual Desire: A Position Statement from the Brazilian Society of Endocrinology and Metabolism
Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.
research Acne Protection: Measures and Miseries
Acne can be managed with various treatments and requires psychological support due to its emotional impact.
research Androgens in Women: Critical Evaluation of Methods for Their Determination in Diagnosing Endocrine Disorders
The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.
research Sex Differences in the Hypothalamic–Pituitary–Adrenal Axis’ Response to Stress: An Important Role for Gonadal Hormones
Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
research Generation of Tβ4 Knock-In Cashmere Goat Using CRISPR/Cas9
Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.
research Hormonal Trends in Patients Suffering from Long COVID Symptoms
Long COVID patients may have hormonal imbalances linked to their symptoms.
research Investigation, Treatment, and Monitoring of Late-Onset Hypogonadism in Males: ISA, ISSAM, and EAU Recommendations
Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.
research The Hair Follicle: Functions, Self-Renewal, and Alopecic Disorders
Dogs could be good models for studying human hair growth and hair loss.
research Melatonin Induces a Stimulatory Action on the Scrotal Skin Components of Soay Ram in the Non-Breeding Season
Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.
research The Many Faces of Calcineurin Inhibitor Toxicity—What the FK?
Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.
research Piperine Reduces Hair Oiliness by Inhibiting Adipogenesis of Hair Stem Cells
Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.
research Detection of Urine Metabolites in Polycystic Ovary Syndrome by UPLC Triple-TOF-MS
Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.
research Abstracts from the ASA 40th Annual Meeting
HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.
research Advances in Male Hormone Substitution Therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Dual Deficiency of Melatonin and Dihydrotestosterone Promotes Stromal Cell Damage and Mediates Prostatitis via the cGAS-STING Pathway in Sleep-Deprived Mice
Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.