1 citations
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September 2025 in “Journal of Cosmetic Dermatology” This study introduces the "skinspan" framework to promote skin longevity through sun protection, topical retinoids, and antioxidants as first-line care. It suggests lasers and emerging therapies as additional options but emphasizes the need for more randomized controlled trials to solidify the evidence base.
6 citations
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February 2022 in “European journal of endocrinology” This study developed a validated method using UPLC-MS/MS to analyze 37 hormones in human hair, enabling broader hormonal profiling for identifying endocrine disorders.
This study found that activation of delta-opioid receptors in keratinocytes may delay the expression of the PER2 gene, suggesting a possible link to cancer development through circadian rhythm disruption.
62 citations
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August 2014 in “BMC Endocrine Disorders” This review summarizes the recent advances in molecular mechanisms influencing tissue sensitivity to glucocorticoids, emphasizing novel mutations and new information on the glucocorticoid receptor's circadian rhythm and ligand-induced repression, but reports no new results.
12 citations
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January 2019 in “Sleep medicine” This study found that night shift work disrupts clock gene expression in Japanese men, particularly affecting rhythms and levels of Period3 and Nr1d2, based on the shift schedule.
68 citations
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April 2012 in “Journal of Investigative Dermatology” The study reports that Fgf18 and Tgf-β2 signaling pathways in hair follicle stem cells have opposing effects on the timing of hair cycle transitions, influencing the shift from telogen to anagen phases.
October 2017 in “The American Journal of Gastroenterology” This case report details a 71-year-old man diagnosed with Cronkhite-Canada Syndrome, highlighting the importance of early diagnosis and endoscopic evaluation due to the disease's progressive nature and significant mortality risk.
43 citations
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July 1984 in “Clinical and Experimental Dermatology” This study found that women with common baldness treated with cyclical antiandrogen therapy for 52 weeks experienced increased hair density and a higher percentage of hairs in the anagen growth phase.
In this study, researchers assessed the stability of various formulations in the TrichoConcept™ line for customized alopecia treatment. They found that the combinations remained stable from 14 to 180 days, supporting the use of these vehicles for enhancing therapeutic outcomes in hair loss treatments.
August 2025 in “The Nishinihon Journal of Dermatology” In this case study, a 53-year-old male diagnosed with Cronkhite-Canada syndrome saw improvements in diarrhea and hair regrowth after starting treatment with prednisolone, and a year later, all polyps had disappeared, suggesting a potential link between the syndrome and Alopecia areata incognita.
85 citations
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January 2018 in “Cell stem cell” This study found that synchronized signals in the microenvironment regulate stem cell lineage choices in hair follicles by influencing chromatin dynamics during regeneration.
March 2025 in “Institutional Repositories DataBase (IRDB)” This review discusses the potential and limitations of using hair cortisol as a measure of chronic stress, noting that its effectiveness depends on recognizing patterns rather than absolute cortisol levels.
2 citations
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March 2004 in “Journal of the American Academy of Dermatology” This study found that a 60-second timed hair count is a practical and reproducible method for women to document hair shedding and treatment response at home, with significant differences in hair shedding observed between age groups in follow-up results.
1 citations
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June 2015 in “Australasian Journal of Dermatology” This case report describes a patient with Cronkhite–Canada syndrome, where immunosuppression and nutritional support led to disease remission.
July 2024 in “Journal of Investigative Dermatology” Scalp cooling may be less effective for women of color on certain chemotherapy treatments.
This study aims to describe the trichoscopic pattern of chemotherapy-induced alopecia and its changes during different phases of chemotherapy.
59 citations
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December 2016 in “Supportive Care in Cancer” This study found that symptom clusters in patients undergoing chemotherapy for breast cancer are stable over time, suggesting that targeting core symptoms may help reduce symptom burden.
50 citations
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May 2020 in “FEBS Letters” This review discusses techniques for analyzing the cell cycle, highlighting emerging tools for measuring cell cycle speed at single-cell resolution in live animals, and reports no new results.
December 2025 in “Aesthetic Cosmetology and Medicine” This study emphasizes the need for personalized hair care strategies based on in-depth diagnostics, taking into account scalp type, environmental factors, and the microbiome, suggesting that this holistic approach could improve hair condition.
January 2023 in “Endocrine Journal” This review discusses the challenges in optimizing glucocorticoid treatment for classic 21-hydroxylase deficiency, emphasizing individualized care and the need for comprehensive management, but presents no new findings.
November 2024 in “Journal of Investigative Dermatology” Paclitaxel chemotherapy causes premature aging and damage to hair follicles, potentially leading to permanent hair loss.
4 citations
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May 2022 in “Journal of Nepal Medical Association” This case report describes a 40-year-old woman with Cronkhite-Canada Syndrome whose symptoms, including gastrointestinal issues and skin changes, improved significantly with corticosteroids, co-infection treatment, and nutritional counseling.
October 2013 in “The American Journal of Gastroenterology” This case study reports a diagnosis of the rare Cronkhite-Canada syndrome in a 60-year-old man, who showed symptom improvement following treatment with prednisone and azathioprine.
January 2022 in “Gastro Hep advances” This case report describes a woman diagnosed with Cronkhite-Canada syndrome whose gastrointestinal symptoms and alopecia improved significantly after systemic prednisone treatment, with no recurrence four years after a second treatment course.
1 citations
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January 2016 in “Journal of Biosciences and Medicines” This study found that the ACTH/MC2R system is important for hair cycle regulation, with deficiencies in MC2R leading to altered hair growth phases in mice.
February 2024 in “medRxiv (Cold Spring Harbor Laboratory)” This study aims to assess how daily life factors affect sleep patterns and describe individual sleep changes across the year, with results to be published in future research.
221 citations
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July 2012 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that the circadian clock in mouse skin regulates cell proliferation and affects sensitivity to UVB-induced DNA damage, with potential implications for understanding human skin cancer risk.
13 citations
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December 2010 in “Nature Reviews Endocrinology” A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.
February 2017 in “Cancer Research” In this study involving women undergoing taxane-based chemotherapy, a twice-daily topical application of BPM31543 was well-tolerated and showed potential in reducing severe hair loss, prompting further investigation at higher doses.
December 2024 in “PubMed” This study evaluates the compatibility of six active pharmaceutical ingredients, including finasteride and spironolactone, with TrichoFoam™, a foam vehicle used in personalized treatments for alopecia, though it does not report specific results.