Scalp Cooling for Chemotherapy-Induced Alopecia in Skin of Color Patients: An Interventional Study

    Daniel Alicea, William A. Robinson, Yasmine Oprea, Kosaku Shinoda, Y. Halberstam, D. Hasgood, Beth N. McLellan
    TLDR Scalp cooling may be less effective for women of color on certain chemotherapy treatments.
    This study investigates factors predicting the cessation of scalp cooling (SC) in women of color undergoing chemotherapy for breast or non-small cell lung cancer. Among 13 participants, factors associated with SC discontinuation included cyclophosphamide or immunotherapy treatment (p=.0047) and higher taxane-based chemotherapy doses (p=.05). No significant differences were found regarding ethnicity, hair type, family cancer history, smoking status, alcohol usage, or age. The study highlights the need for further research to determine if these factors also affect SC efficacy, emphasizing the importance of understanding SC's role in addressing disparities in cancer outcomes.
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