research Exosomes for Repair, Regeneration, and Rejuvenation
Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
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research Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence
Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
research Local Heroes or Villains: Tissue-Resident Memory T Cells in Human Health and Disease
Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
research Role of Stearoyl-CoA Desaturase-1 in Skin Integrity and Whole Body Energy Balance
SCD1 is crucial for skin health and overall energy balance.
research Vitamin D And Skin Diseases: A Review
Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.
research Polycystic Ovary Syndrome and Its Differential Diagnosis
The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
research Surrogate End-Points or Primary Outcomes in Clinical Trials in Women with Polycystic Ovary Syndrome?
The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
research Cellular Senescence in Tissue Repair: Every Cloud Has a Silver Lining
Cell aging can be both good and bad for tissue repair.
research Autoimmune Polyendocrine Syndrome Type 1: An Italian Survey on 158 Patients
APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.
research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
research Adipose Stem Cells From Type 2 Diabetic Mice Exhibit Therapeutic Potential In Wound Healing
Fat stem cells from diabetic mice can still help heal wounds.
research Major Improvement in Wound Healing Through Pharmacologic Mobilization of Stem Cells in Severely Diabetic Rats
A new therapy sped up wound healing and reduced scarring in diabetic rats.
research A Japanese Case of Ichthyosis Follicularis with Atrichia and Photophobia Syndrome with an MBTPS2 Mutation
A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.
research Skin Manifestations Associated With Systemic Diseases – Part I
The conclusion is that early diagnosis of skin signs linked to diseases like Lupus, Dermatomyositis, and Rheumatoid Arthritis is crucial to prevent serious complications.
research The Inflammatory Aspect of Male and Female Pattern Hair Loss
Inflammation affects hair loss; anti-inflammatory treatments may help.
research Risk Factors, Prevalence, and Diagnosis of Hutchinson-Gilford Syndrome with Special Reference to Case Reports
Hutchinson-Gilford Progeria Syndrome is a rare genetic disorder caused by a specific gene mutation, characterized by aging symptoms and managed by monitoring heart health and using low-dose aspirin.
research Skin Fibroblast Functional Heterogeneity in Health and Disease
Different types of skin fibroblasts have unique roles in skin health and disease.
research The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring
PBMCsec can help reduce and improve thick skin scars.
research Human Regulatory T Cells: Role in Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers
Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
research The Role and Prospects of Mesenchymal Stem Cells in Skin Repair and Regeneration
Mesenchymal stem cells show promise for effective skin repair and regeneration.
research Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity: Lessons from Alopecia Areata
ILC1-like cells can cause alopecia areata by attacking hair follicles.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research The Rotterdam Study: 2016 Objectives and Design Update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Careless Talk Costs Lives: Fibroblast Growth Factor Receptor Signalling and the Consequences of Pathway Malfunction
Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
research C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin
C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Immune Modulation of Hair Follicle Regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.