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The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.

PRP helps hair regrowth and thickness.

Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.

Dermal stem cells help regenerate hair follicles and heal skin wounds.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Oestrogens are key for bone growth during puberty in both boys and girls.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.

Peptide hydrogel scaffolds help grow new hair follicles using stem cells.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.

Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.

Stem cells can help regenerate hair follicles.

3D cell-derived matrices improve tissue regeneration and disease modeling.

Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.

Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.

The document concludes that products like PRP and PRF show promise for tissue healing, but evidence of their effectiveness is inconsistent.