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    Glossary Cholesterol

    waxy substance in cells, crucial for hormones and digestion

    Cholesterol is a waxy, fat-like substance found in every cell of the body, essential for producing hormones, vitamin D, and substances that help digest foods. While the body needs some cholesterol to function properly, high levels of it in the blood can increase the risk of heart disease by contributing to the formation of plaque in arteries.

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    1. Role of cholesterol sulfate in epidermal structure and function: Lessons from X-linked ichthyosis Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2014 · 87 citations
    2. Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin 2010 · 46 citations
    3. The effect of the antiandrogen IIα-hydroxyprogesterone on sebum production and cholesterol concentration of sebum British Journal of Dermatology · 1982 · 27 citations
    4. Cholesterol homeostasis: Links to hair follicle biology and hair disorders Experimental Dermatology · 2019 · 25 citations
    5. Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia PLOS ONE · 2012 · 22 citations
    6. Cholesterol and Phospholipid-free Multilamellar Niosomes Regulate Transdermal Permeation of a Hydrophobic Agent Potentially Administrated for Treating Diseases in Deep Hair Follicles Journal of Pharmaceutical Sciences · 2021 · 14 citations
    7. Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle Histochemistry and Cell Biology · 2021 · 13 citations
    8. Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice Frontiers in Pharmacology · 2021 · 9 citations
    9. The ‘bald’ phenotype (androgenetic alopecia) is caused by the high glycaemic, high cholesterol and low mineral ‘western diet’ Trends in Food Science and Technology · 2021 · 7 citations
    10. Inhibitory effects of cholesterol on cell division in mouse skin: Physicochemical and biological aspects(The problem of male pattern baldness) International Journal of Environmental Studies · 1976 · 7 citations
    11. Jieduquyuziyin prescription alleviates SLE complicated by atherosclerosis via promoting cholesterol efflux and suppressing TLR9/MyD88 activation Journal of Ethnopharmacology · 2023 · 6 citations
    12. Evaluation of methotrexate-loaded surfactants, ceramides and cholesterol-based lamellar phases as a topical treatment for psoriasis Journal of Pharmacy and Pharmacology · 2022 · 2 citations
    13. Multiple desmoplastic trichoepitheliomas with ossification and cholesterol deposition Clinical and Experimental Dermatology · 2009 · 2 citations
    14. Disrupted cholesterol biosynthesis and hair follicle stem cell impairment in the onset of alopecia PLoS ONE · 2025 · 1 citations
    15. DKK1-targeting cholesterol-modified siRNA implication in hair growth regulation Biochemical and Biophysical Research Communications · 2023 · 1 citations
    16. Elevation of serum triglyceride and cholesterol levels from isotretinoin therapy with concomitant oral contraceptives Pharmacoepidemiology and drug safety · 1995 · 1 citations
    17. Cholesterol promotes hair growth through activating sympathetic nerves and enhancing the proliferation of hair follicle stem cells Molecular Medicine · 2025
    18. Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia bioRxiv (Cold Spring Harbor Laboratory) · 2023
    19. Evaluation of Serum Testosterone, Cholesterol and Plasma Glucose Concentrations in Hirsute Women in Bayelsa State Open Journal of Endocrine and Metabolic Diseases · 2022
    20. Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men Journal of lipid research · 2024
    21. Cholesterol homeostasis in hair follicle keratinocytes is disrupted by impaired ABCA5 activity Biochimica and biophysica acta. Molecular and cell biology of lipids · 2023
    22. Inhibition of Cholesterol Biosynthesis Modulates Epithelial-Mesenchymal Transition in Primary Cicatricial Alopecia Through TGFβ and Angiotensin Receptors Journal of Endocrinology and Reproduction · 2023
    23. 865 Frontal fibrosing alopecia is associated with dysregulation of cholesterol biosynthesis pathways, fibrosis and mast cells Journal of Investigative Dermatology · 2019
    24. 863 Central centrifugal cicatricial alopecia gene expression analysis revealed cholesterol, fatty acid, and mast cell pathways 2019
    25. 923 Molecular phenotyping of lichen planopilaris revealed dysregulation of cholesterol/fatty acid metabolism, fibrosis and mast cell pathways Journal of Investigative Dermatology · 2019
    26. SHORT-TERM DIABETES IN THE BRAIN: EFFECTS ON NEUROACTIVE STEROIDS, CHOLESTEROL HOMEOSTASIS, AND MITOCHONDRIAL FUNCTIONALITY Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · 2017
    27. Low sex hormone-binding globulin is associated with low high-density lipoprotein cholesterol and metabolic syndrome in women with PCOS Human Reproduction · 2006 · 71 citations
    28. Both low circulating insulin-like growth factor-1 and high-density lipoprotein cholesterol are associated with hair loss in middle-aged women British Journal of Dermatology · 2016 · 6 citations
    29. Finasteride Reduces Total Cholesterol in LDLR-Deficient Mice Current developments in nutrition · 2021
    30. Coronavirus Infection and Cholesterol Metabolism Frontiers in Immunology · 2022 · 55 citations