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We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Compounds from Jatropha cordata bark have significant anti-inflammatory effects and could help with hair loss.

Marine microbes could be used in cosmetics for sun protection, skin care, and possibly preventing hair loss.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Finasteride negatively affects fish reproduction and gonadal development.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

New treatments for skin diseases are more effective and patient-friendly, but many still lack a cure.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Annurca apple supplement safely increases hair growth and keratin in humans.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.