research NUDT15, FTO, and RUNX1 Genetic Variants and Thiopurine Intolerance Among Japanese Patients With Inflammatory Bowel Diseases
Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.
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research Adverse Events of Non-Ablative Fractional Laser Photothermolysis: A Retrospective Study of 856 Treatments in 362 Patients
Non-ablative fractional laser treatments have a low risk of side effects in Asian patients.
research The Evaluation of IL-4 Intron 3 VNTR and TNF-α (rs1799964) Gene Polymorphisms in Egyptian Patients with Alopecia Areata: A Case-Control Study
These specific gene polymorphisms are not linked to Alopecia Areata in Egyptians.
research Associations Between Serum Dihydrotestosterone Levels, Lipid Parameters, and Anthropometric Measurements in Male Patients with Type 2 Diabetes Mellitus
Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.
research Target-Adverse Events and Fear of Cancer Progression, Anxiety, and Depression in Patients with Advanced Non-Small Cell Lung Cancer
Adverse events in lung cancer treatments increase fear, anxiety, and depression, with newer therapies causing fewer side effects.
research Incidence of Adverse Cutaneous Drug Reactions in a Mexican Sample: An Exploratory Study on Their Association to Tumor Necrosis Factor Alpha TNF2 Allele
Mexican patients had a lower incidence of skin reactions to drugs and no significant link between these reactions and the TNF2 gene variant.
research Self-Concept and Body Image of People Living with Lupus: A Systematic Review
Lupus patients' body image issues significantly affect their mental health and need more support.
research Quality of Life Assessment in Patients with Alopecia Areata and Androgenetic Alopecia in the People's Republic of China
Hair loss from alopecia areata and androgenetic alopecia moderately affects the quality of life, especially in younger patients and those with long-term hair loss, impacting both their physical and emotional well-being.
research Quality of Life of Patients with Metastatic Breast Cancer Treated with Epirubicin and Docetaxel
Patients with metastatic breast cancer treated with epirubicin and docetaxel had a good response and maintained their quality of life.
research Safety and Patient-Reported Outcomes in Patients With Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer Treated With CDK4/6 Inhibitors in China: A Cross-Sectional Study
Dalpiciclib is the safest and most satisfying CDK4/6 inhibitor for advanced breast cancer patients in China.
research Severe Diffuse Non-Scarring Hair Loss in Systemic Lupus Erythematosus: Clinical and Histopathological Analysis of Four Cases
Hair loss in systemic lupus erythematosus patients is unique and improves with treatment.
research Efficacy and Safety of Baricitinib in Patients With Refractory Alopecia Areata
Baricitinib helped some patients with tough-to-treat hair loss regrow hair, but more research is needed on its safety.
research Post-Covid-19 Syndrome and Quality of Life Impairment in Severe Covid-19 Mexican Patients
Most severe COVID-19 patients in Mexico experienced long-lasting symptoms that worsened their quality of life.
research Drug Survival and Long-Term Outcome of Tofacitinib in Patients with Alopecia Areata: A Retrospective Study
Tofacitinib is effective and safe for treating alopecia areata with a good drug survival rate.
research Randomized Trial of Microneedling Combined With 2% Minoxidil Topical Solution for the Treatment of Female Pattern Hair Loss in a Chinese Population
Combining microneedling with 2% minoxidil is more effective and safe for treating female pattern hair loss than using minoxidil alone.
research Adherence Patterns to Medications and Their Association with Subsequent Hospitalization in Adult Egyptian Patients with Systemic Lupus Erythematosus
Non-adherence to medication in Egyptian SLE patients leads to more hospitalizations and symptoms.
research Effects of Androgen Treatment on Growth in Patients with 5-Alpha-Reductase Type 2 Deficiency
Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.
research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research Repigmentation of Leukoderma in a Piebald Patient Associated with a Novel c-KIT Gene Mutation, G592E, of the Tyrosine Kinase Domain
A new gene mutation may allow some piebaldism patients to regain skin color in white patches.
research Two Novel BTD Mutations Causing Profound Biotinidase Deficiency in a Chinese Patient
The study found two new mutations in a Chinese patient with severe biotinidase deficiency.
research Prevalence of Low Serum Vitamin D Levels in Patients Presenting With Androgenetic Alopecia: A Review
Low vitamin D levels are linked to hair loss, and vitamin D might help treat it.
research Cutaneous Toxicity as a Predictive Biomarker for Clinical Outcome in Patients Receiving Anticancer Therapy
Skin reactions from cancer treatments might predict how well the treatments work.
research Adverse Events Associated with Azathioprine Treatment in Korean Pediatric Inflammatory Bowel Disease Patients
Azathioprine caused side effects in over half of the Korean pediatric inflammatory bowel disease patients, requiring close monitoring.
research Case Report: A Novel Splice-Site Mutation of MTX2 Gene Caused Mandibuloacral Dysplasia Progeroid Syndrome: The First Report from China and Literature Review
A new MTX2 gene mutation caused a severe genetic disorder in a young Chinese girl.
research Feasibility and Tolerability of Eribulin-Based Chemotherapy Versus Other Chemotherapy Regimens for Patients With Metastatic Triple-Negative Breast Cancer: A Single-Center Retrospective Study
Eribulin-based chemotherapy is more effective and has fewer side effects for advanced triple-negative breast cancer.
research Recurrent Toxic Hepatitis in a Caucasian Girl Related to the Use of Shou-Wu-Pian, a Chinese Herbal Preparation
A 5-year-old girl had liver damage twice after using the herbal product Shou-Wu-Pian.
research Analysis of a Multiple Nuclear Dots Pattern in a Large Cohort of Dermatological Patients
Anti-MND antibodies are present in various diseases, not just PBC, and their levels don't correlate with disease activity or skin symptoms.
research The Role of Candidate Pharmacogenetic Variants in Determining Valproic Acid Efficacy, Toxicity, and Concentrations in Patients with Epilepsy
Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.
research The Relation Between Vitiligo and Other Autoimmune Disorders
Vitiligo is often found with other autoimmune diseases, which is important to know to help patients.
research Incidence and Risk Factors for Neonatal Occipital Alopecia: A Retrospective Study
Babies born after 38 weeks to mothers under 36 years old and not delivered by C-section have a higher risk of neonatal occipital alopecia.