Efficacy and Safety of Baricitinib in Patients With Refractory Alopecia Areata

    September 2022 in “ Dermatologic Therapy ”
    Yuqian Wang, Taoming Liu, Sheng Li … Hong Fang
    Studysummary This study found that twice-daily oral baricitinib at a 2-mg dose showed promising results in treating refractory alopecia areata, particularly among Chinese patients, with 64% achieving significant hair regrowth, although none attained complete hair regrowth. Adverse events were mild and included nausea and folliculitis.
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    Research cited in this study 7

    1. Two Phase 3 Trials of Baricitinib for Alopecia Areata The New England Journal of Medicine · 2022
    2. The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications Cells · 2021
    3. Efficacy and Safety of the Oral Janus Kinase Inhibitor Baricitinib in the Treatment of Adults with Alopecia Areata: Phase 2 Results from a Randomized Controlled Study Journal of The American Academy of Dermatology · 2021
    4. New and Emerging Therapies for Alopecia Areata Drugs · 2020
    5. JAK Inhibition in the Treatment of Alopecia Areata: A Promising New Dawn? Expert review of clinical pharmacology · 2019
    6. JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    7. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017

    Related research 4

    1. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    2. Linear Alopecia Areata JAAD case reports · 2018
    3. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018
    4. Topical Minoxidil for the Treatment of Alopecia Areata PubMed · 2017