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90-120 / 1000+ resultsresearch The application of an oral zinc tolerance test to assess zinc absorption from three different dietary sources in the dog
This review discusses zinc's role in dog metabolism and suggests that zinc from amino acid chelates might be better absorbed than from inorganic sources, but reports no new experimental results.
research Microencapsulating Alginate-Based Polymers for Probiotics Delivery Systems and Their Application
This review discusses alginate-based delivery systems for probiotics, highlighting recent advances, challenges, and future directions, but reports no new clinical findings.
research Injectable Biomaterials for Dental Tissue Regeneration
This narrative review discusses the role of injectable biomaterials in dental tissue regeneration, highlighting their suitability for treating small, hard-to-access oral defects compared to pre-formed scaffolds, and explores the potential use of nanofibers in dental applications.
research Development and In Vitro Characterization of Neusilin® US2-Based Solid Self-Nanoemulsifying Drug Delivery System for Oral Administration of Finasteride
This study developed a Neusilin® US2-based solid self-nanoemulsifying drug delivery system for finasteride that showed improved stability and drug delivery, with complete dissolution comparable to standard Propecia® tablets.
research HPTLC assay of nicotine and cotinine in biological samples
This study developed a straightforward HPTLC method for detecting nicotine and cotinine in human plasma and urine, concluding that liquid-liquid extraction with methanol: chloroform: ammonia achieved optimal separation and is applicable for forensic analysis of lethal nicotine intoxication.
research The application of an oral zinc tolerance test to assess zinc absorption from three different dietary sources in the dog
This review discusses zinc's role in dog nutrition, emphasizing that zinc absorption may be improved when provided as an amino acid chelate rather than an inorganic source, but reports no new results.
research An Overview of Chitosan-Based Composites Containing Silver or Zinc Oxide Nanoparticles: Antimicrobial and Antibacterial Properties, and Biomedical Perspectives
This study reviewed chitosan composites, specifically those with silver or zinc oxide nanoparticles, highlighting their enhanced antimicrobial efficacy and potential biomedical applications despite pure chitosan's limitations such as pH sensitivity and poor solubility.
research Design of a gelatin microparticle-containing self-microemulsifying formulation for enhanced oral bioavailability of dutasteride
This study found that a gelatin microparticle-containing self-microemulsifying formulation combined with Soluplus improved the oral absorption of dutasteride.
research Synthesis, physical characteristics, and biocompatibility test of chitosan-alginate-fucoidan scaffold as an alternative material for alveolar bone substitution
In this study, researchers explored the use of natural materials in scaffold construction for dental bone preservation, suggesting it could offer better biocompatibility and bone regeneration compared to traditional grafting methods.
research أدوية الإقلاع عن التدخين
In this study, the researchers found that using computers and modern technologies can aid smoking cessation efforts, highlighting that smoking cessation medications and informed awareness can help reduce smoking and its associated harms, which include severe health risks like cancer and heart disease.
research Formulation and evaluation of self-nanoemulsifying drug delivery system for improved oral delivery of exemestane hydrochloride
This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.
research Drug–Drug Coamorphous System of Tadalafil and Finasteride for Enhanced Pharmaceutical Performance
In this study, researchers developed a coamorphous form of tadalafil and finasteride, showing improved solubility and dissolution in vitro, with results successfully translated in vivo in rats. They reported reasonable stability, suggesting this form could serve as a therapeutic alternative to the current marketed combination.
research Hollow-adjustable polymer microneedles for prolonged hypoglycemic effect on diabetic rats
research The Potential Teeth Bleaching and Halitosis Prevention Effects of Pediococcus inopinatus THK-30, a Kimchi-Derived Lactic Acid Bacterium: In Vitro Study
This study demonstrated that a strain of lactic acid bacteria from kimchi, identified as Pediococcus inopinatus, showed antibacterial activity against certain oral pathogens and effectively bleached stained artificial teeth and inhibited biofilm formation, offering potential for addressing teeth discoloration and halitosis.
research Development of an improved method to estimate the days of continuous drug ingestion, based on the micro‐segmental hair analysis
This study improved a hair analysis method to estimate the days of continuous ingestion of hay-fever medicines, with an average error of about 2 days from actual ingestion.
research What's New: Newly Approved Drugs for Children
This article reviews 12 newly approved drugs with pediatric indications from 2001, discussing their clinical importance for general pediatricians, but reports no new clinical results.
research Application of Scaffold-Based Drug Delivery in Oral Cancer Treatment: A Novel Approach
This review highlights the potential of scaffold-based drug delivery systems to revolutionize oral cancer treatment by enhancing targeted and localized drug administration, reducing systemic side effects, and providing environments conducive to non-cancerous cell growth, though challenges like scalability and biocompatibility remain.
research CARAWAY, CHINESE CHIVES AND CASSIA AS FUNCTIONAL FOODS WITH CONSIDERING NUTRIENTS AND HEALTH BENEFITS
This review discusses the medicinal and health benefits of caraway, Chinese chives, and cassia, focusing on their antibacterial, antioxidant, antimicrobial, anti-inflammatory, and anticancer properties due to their range of secondary metabolites.
research Formulation of a film-coated dutasteride tablet bioequivalent to a soft gelatin capsule (Avodart®): Effect of γ-cyclodextrin and solubilizers
This study found that a dutasteride tablet formulation using cyclodextrin complex, solubilizing polymer, and surfactant achieved similar bioavailability in beagle dogs to that of a commercial capsule.
research Fast-tracked innovation: orforglipron approval under the FDA’s National Priority Voucher program
This study highlights the approval of orforglipron under the FDA's National Priority Voucher program, emphasizing its significance as a convenient oral treatment option with beneficial effects on glycemic and lipid profiles for diabetes and obesity management.
research Swellable Microneedles in Drug Delivery and Diagnostics
This review examines the potential of swellable microneedles in drug delivery and diagnostics, highlighting innovations and challenges in their use for chronic disease treatment, but noting that issues like physiological responsiveness and long-term stability still require research.
research Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: From potassium channel openers to calcium entry blockers?
This study found that several newly synthesized dihydrobenzopyran compounds inhibited insulin secretion and had vasorelaxant activity, with some more potent than reference KATP channel activators, though compound 21 functioned as a Ca2+ entry blocker.
research EFFICACY AND SAFETY OF STANDARDIZED CINNAMON BARK EXTRACT FOR THE PREVENTION OF CHEMOTHERAPY-INDUCED WEIGHT LOSS AND ALOPECIA IN PATIENTS WITH BREAST CANCER: A RANDOMIZED, DOUBLE-BLIND, AND PLACEBO-CONTROLLED STUDY
This study found that in female breast cancer patients, supplementation with 400 mg IND02 (Cinnamon bark extract) thrice daily during chemotherapy significantly reduced severe weight loss and hair loss compared to placebo, with the treatment being well-tolerated and safe.
research Pharmacological and Biological Efficacy of Chitosan-Based Materials
This review reports that chitosan, a versatile polysaccharide, shows potential for various therapeutic applications due to its chemical modifications, notably in treating non-communicable diseases and wound healing, though further clinical study is needed to confirm these benefits.
research Preparation of Nanochitin from Crickets and Comparison with That from Crab Shells
In this study, cricket-derived chitin successfully converted to nanochitin, which demonstrated improved physical properties such as higher transmittance and greater modulus compared to crab shell nanochitin.
research Effect of Chlorhexidine Digluconate in Early Wound Healing of Human Gingival Tissues. A Histological, Immunohistochemical and Biomolecular Analysis
This study observed that post-surgical use of chlorhexidine digluconate mouth rinse in patients may induce a fibrotic transformation in gingival tissue, promoting a scar-like wound healing response.
research Chitosan stimulates root hair callose deposition, endomembrane dynamics, and inhibits root hair growth
This study found that in Arabidopsis root hairs, mild chitosan treatment triggered callose deposition and slowed growth, while a higher concentration inhibited growth without callose deposition, indicating different responses based on chitosan concentration.
research The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil
research MICRO-URZĄDZENIA, BEZPRZEWODOWE KAPSUŁKI, MAPY, STYMULATORY I ROZRUSZNIKI STOSOWANE DO DIAGNOSTYKI I LECZENIA ZABURZEŃ MOTORYKI PRZEWODU POKARMOWEGO
This source provides an overview of diagnostic and treatment innovations for gastrointestinal disorders, such as wireless capsule technology for motility assessment and new methods for treating constipation and nausea, highlighting both current and emerging techniques.