May 2024 in “International journal of medicine and psychology.” This study discusses key issues in organizing effective mediation services within educational institutions, highlighting the need for regulatory clarity and professional communication, and addressing common misconceptions about the role of mediation services when no mediation cases are requested.
May 2024 in “The Journal of Immunology” In a mouse model of alopecia areata, this study found that IL-27 overexpression using an adeno-associated virus protected against disease development, potentially by promoting immunosuppressive T cells and reducing CD8 T cell infiltration into hair follicles.
This study found that the transcription factor Meis2 is crucial for the maturation and innervation of sensory neurons responsible for light touch in mice, with its absence leading to reduced touch sensitivity.
CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.
CaBP1 and CaBP2 are important for continuous hearing by preventing inactivation of calcium currents in ear cells, with CaBP2 also able to restore hearing when reintroduced.
CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.
January 2024 in “Wiadomości Lekarskie” This source analyzes linguistic difficulties faced by speakers of East Slavic languages learning Polish, emphasizing challenges in pronunciation, vocabulary, and grammar. It suggests that tailored educational materials comparing linguistic nuances can improve learning outcomes by highlighting important differences between the languages.
January 2024 in “International Journal of Trichology” In this study, researchers reviewed the evidence linking COVID-19 with dermatologic conditions like androgenetic alopecia and concluded that most proposed associations lack convincing statistical support, challenging the idea of these as independent risk factors for COVID-19 severity.
December 2023 in “British journal of oral & maxillofacial surgery/British journal of oral and maxillofacial surgery” This review discusses the role and function of platelet-rich plasma (PRP) in third molar extractions and reports no new clinical results.
This review reports that alterations in the scalp, hair follicle, and gut microbiome are associated with alopecia, and interventions targeting microbiome dysbiosis may have potential in treating hair loss.
July 2023 in “Journal of the European Academy of Dermatology and Venereology” In a Phase II trial, Cox and colleagues reported that anti-IL17A therapy was well tolerated and led to a 64% reduction in wound size for venous leg ulcers unresponsive to standard treatments, although further validation in a larger trial is needed.
July 2023 in “International journal of trichology” This review concluded that the double-spin PRP preparation method may be more effective than the single-spin technique for treating androgenetic alopecia.
June 2023 in “Journal of multidisciplinary sciences (Online)” This review examines possible links between polycystic ovarian syndrome and reproductive cancers, but reports no new clinical findings.
This study suggests that melatonin may promote hair growth properties by activating the AKT/GSK3β/β-catenin signaling pathway in dermal papilla cells.
January 2022 in “Asian journal of Current Research in Clinical Cancer” This study reviews the potential of dibenzo derivatives as safer cancer treatments but finds conflicting evidence about their effectiveness, possibly due to structural differences among the compounds, and reports no new results.
This study identified the Arabidopsis cation chloride cotransporter CCC1 as essential for regulating pH and function in the trans-Golgi network/early endosome, with its absence causing significant growth and stress response defects.
January 2021 in “Türkiye klinikleri dermatoloji dergisi” This study found that eyebrow involvement in frontal fibrosing alopecia was more common among postmenopausal females with comorbidities, without a significant link to age or disease duration.
This study identified a new isozyme, 5α-reductase-3, at the mRNA level in human prostate tissue, but its protein expression and cellular localization remain unclear.
This study observed that nevus melanocytes do not exhibit signs of senescence, suggesting that their growth arrest is due to cell interactions and not directly caused by BRAF activation.
This study found that IL18 signaling plays a crucial role in the homing and retention of mature regulatory T cells in the mouse thymus, primarily by upregulating the chemokine receptor CCR6.
June 2020 in “Journal of Investigative Dermatology” Hair shaft malformation contributes to Central Centrifugal Cicatricial Alopecia.
In this study, researchers identified IL18R+ thymus-resident regulatory T cells in mice, demonstrating their unique molecular features and resistance to age- and stress-induced thymus involution, highlighting IL18 signaling's role in Treg migration and retention.
This research review concluded that 5α-reductase inhibitors may be effective in treating androgenetic alopecia, showing general efficacy over placebo, though future clinical trials are needed to determine the best drug, dose, and duration, as well as gender differences in treatment response.
February 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, a combination of low-dose minoxidil 0.25 mg and spironolactone 25 mg reduced hair shedding and improved hair density in patients with female pattern hair loss, with mild adverse effects.
This study found that a hair growth rate of 0.75 cm/month better matches retrospective cortisol timelines and identified factors influencing hair cortisol content in children and adolescents.
This study found that fibroblast growth factor 20 (Fgf20) orchestrates the movement and behavior of dermal fibroblasts, directing their formation into dermal condensates during hair follicle development in mice.
This study found that the Arabidopsis thaliana protein Formin 2 localizes to plasmodesmata and is crucial for regulating their permeability by anchoring actin filaments, which affects virus susceptibility.
This study successfully optimized a culture strategy for dermal papilla cells and established an immortalized cell strain, iDP6, which closely resembles primary DP cells in key characteristics.
This study developed and validated an optimized culture method for dermal papilla cells, leading to the establishment of an immortalized cell strain called iDP6, which resembles primary DP cells in key characteristics.
In this study, researchers optimized the culture strategy for dermal papilla cells and established a promising immortalized cell strain, iDP6, which resembles primary DP cells and is suitable for further research applications.