Computational Evaluation of Dibenzo Compounds as Potential Dual Inhibitors of Androgen Receptor and 5α-Reductase
January 2022
in “
Asian journal of Current Research in Clinical Cancer
”
TLDR Some dibenzo compounds might help treat cancer with fewer side effects.
The study evaluated dibenzo compounds as potential dual inhibitors of the androgen receptor and 5α-reductase, which were relevant in cancer treatment. While some dibenzo derivatives showed promise, there were conflicting reports about their efficacy, possibly due to structural differences. The research aimed to clarify these inconsistencies to identify safer treatment options with fewer side effects like high blood pressure, liver damage, and erectile dysfunction.