In this study, researchers found that the bioactive lipid sphingosine 1-phosphate and its receptor, S1PR3, are essential for regulating mechanical pain sensitivity in mice.
This study found that IL-1α and IL-7 secreted from keratinocytes in a genetically engineered mouse model can stimulate the expansion of γδT-cells, aiding in the proliferation of epidermal stem cells for wound healing.
This study found that the crude extract of Hibiscus rosa-sinensis leaves, whether irradiated or not, showed significant antioxidant activity without causing toxicity in rats, suggesting gamma radiation may enhance its therapeutic properties.
This study found that type XVII collagen (COL17) regulates interfollicular epidermis proliferation in both neonatal and aged mice through Wnt signaling, suggesting its potential as a target for anti-aging skin strategies.
This study found that type XVII collagen is crucial for regulating epidermal cells' proliferation in mice and may be a promising target for anti-aging skin treatments.
March 2017 in “International Society of Hair Restoration Surgery” Female hair loss may be linked to heart health and aging.
November 2016 in “Faridpur Medical College Journal” This study observed that Betamethasone oral mini-pulse therapy showed a good response in 60% of lichen planus patients, though further research is needed to confirm its efficacy.
This study found that the NuMA protein's microtubule-binding domain is essential for proper spindle orientation and differentiation in keratinocytes, affecting skin and hair development in mice.
This review discusses the potential association between vaccination and alopecia areata, highlighted in case reports, notably with the hepatitis B virus vaccine, but provides no new results.
This study found that bursts of ERK activation in the epidermis of mice were linked to cell division, supporting synchronized cell proliferation and transient ERK activity in living tissues.
October 2014 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” This study identified a new subset of Ret-positive sensory neurons involved in itch perception, characterized by their unique expression profile and response to specific itch-inducing molecules.
March 2013 in “International Society of Hair Restoration Surgery” This article addresses recent negative publicity around finasteride for hair loss and notes an increase in patients choosing topical alternatives, without presenting new research findings.
December 2011 in “Ophthalmology” This article discusses the potential association between Demodex and blepharitis but reports no new findings, as the authors evaluated systemic associations without data on Demodex infestation.
September 2011 in “Cancer” This study found that men who began balding at age 20 were twice as likely to develop prostate cancer later in life compared to those who did not experience early hair loss.
July 2011 in “Hair transplant forum international” This article discusses the potential of green tea to treat iron overload by reducing iron absorption, based on a clinical case from the author's practice, and reports no new findings.
March 2011 in “Focus on surfactants” Several companies launched new hair care ingredients in 2011 to improve conditioning, color retention, combability, and heat protection.
January 2011 in “Yearbook of Dermatology and Dermatologic Surgery” Thicker melanomas and nodular types are more likely to spread to sentinel lymph nodes.
September 2009 in “Annales D Endocrinologie” This article reviews the clinical signs, diagnostic approaches, and treatment options for hyperandrogenism in women, focusing on hirsutism and specifies that cyproterone acetate is effective for severe cases, but reports no new clinical results.
March 2007 in “Journal of Cell Science” This study found that keratin K1014chim expression in mice did not reduce epidermal cell proliferation but increased susceptibility to benign tumors, challenging previous beliefs about K10's role in inhibiting tumor development.
August 2005 in “British journal of dermatology/British journal of dermatology, Supplement” This article replies to a critical appraisal of a randomized trial on melatonin in alopecia and reports no new clinical findings.
This review discusses recent advances in understanding the molecular mechanisms of hair generation and regeneration, with an emphasis on androgenetic alopecia and alopecia areata, and anticipates new therapies, but reports no new results.
January 2004 in “Anticancer Research” This study suggested that long-term finasteride treatment for BPH patients may induce neuroendocrine activity in the prostate, potentially increasing the risk of developing aggressive prostate cancer.
July 2003 in “Pediatrics in review” This article reviews 12 newly approved drugs with pediatric indications from 2001, discussing their clinical importance for general pediatricians, but reports no new clinical results.
December 1999 in “Dermatologic Surgery” Experts discussed sedation, hair transplant techniques, and called for respectful professional communication.
January 1999 in “대한피부과학회지” This study aimed to explore the relationship between stress and dermatologic disorders and found that the connection remains unclear, but it also examined the potential influence of coping strategies.
February 1994 in “Archives of Dermatology” This article critiques the limited clinical applicability of recognizing catagen in hair cycle studies, emphasizing its importance in histologic diagnosis and the continuum with telogen effluvium.
January 1983 in “Journal of The American Academy of Dermatology” The document suggests improvements for a hair and scalp disease book and recommends a two-volume skin surgery reference for dermatologists.
November 1978 in “PubMed” This review discusses the role of antiandrogenic gestagens in treating androgen-dependent skin disorders and highlights the need for dermatologists to collaborate with endocrinologists and gynecologists for effective management.
December 1977 in “Archives of Dermatology” This letter discusses prior findings on prednisone for alopecia areata, agreeing that systemic steroids usually do not change the disease course but contesting that most patients have a poor prognosis.
January 1972 in “Open PRAIRIE (South Dakota State University)” This research explored potential mechanisms for the toxicity of mimosine but did not identify a conclusive reason for its adverse effects.