Cyberspace Chat: Topical Minoxidil and Association with Cardiac Arrhythmia

March 2013 in “ International Society of Hair Restoration Surgery ”

Sharon A. Keene

topical minoxidil finasteride cardiac arrhythmia hair loss treatment Rogaine Propecia

From the encyclopedia

Frontline, gold standard treatment for combatting androgenic alopecia

An essential vasodilator with some anti-androgenic effects

Studysummary This article addresses recent negative publicity around finasteride for hair loss and notes an increase in patients choosing topical alternatives, without presenting new research findings.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

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research A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss

219 citations , March 2004 in “Journal of The American Academy of Dermatology”

In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.

research A Case of Acute Myocardial Infarction Associated with Topical Use of Minoxidil for Treatment of Baldness

15 citations , January 2000 in “Japanese Heart Journal”

This case report discusses a 45-year-old Japanese man who developed myocardial infarction while using 1% topical minoxidil for baldness, highlighting the need for caution in patients with cardiovascular disorders.

research Topical Minoxidil: Cardiac Effects in Bald Men

45 citations , October 1988 in “British Journal of Clinical Pharmacology”

This study found that topical minoxidil increased heart rate and had significant effects on cardiac volumes and mass compared to placebo, but its long-term safety remains uncertain.