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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Mice with autoimmune hair loss showed signs of heart problems.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.

Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Genetics play a role in acne, but how exactly they contribute is not fully understood.