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Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Stem cells can be primed to respond faster to injury through mTORC1 signaling, enhancing muscle regeneration.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.

A special environment is needed to fully activate sleeping stem cells.

Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Certain immune cells in the skin can stop hair from growing.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Polycomb Repressive Complex 2 is not needed for hair regeneration.

EGFR is crucial for preventing hair follicle inflammation and hair loss.

Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Lactate production is important for activating hair growth stem cells.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Different types of skin cells play specific roles in development, healing, and cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Muscles and nerves that cause goosebumps also help control hair growth.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.

CIP/KIP proteins help stop cell division and support hair growth.