12 citations
,
February 2014 in “Recent Patents on Inflammation & Allergy Drug Discovery” This article reviews various aspects of shampoos, including preparation methods and commercial value, but reports no new experimental results, instead focusing on patents and product evaluation criteria.
10 citations
,
May 2021 in “Expert Opinion on Drug Delivery” This study found that CoQ10 formulated in transethosomes showed improved penetration and a better clinical response in treating androgenic alopecia compared to CoQ10 solution.
10 citations
,
June 2018 in “Aaps Pharmscitech” The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
9 citations
,
August 2024 in “Cureus” This study reviewed existing knowledge and research, observing that ketoconazole shampoo is a safe and effective treatment for scalp seborrheic dermatitis, significantly improving irritation and scaling while maintaining low relapse rates and minimal side effects.
7 citations
,
June 2020 in “Experimental dermatology” This study identified key lipid differences between black and white hair in individuals with premature greying, highlighting vitamin D3 as a potential target for further research in understanding this condition.
5 citations
,
October 2025 in “International Journal of Nanomedicine” This review discusses the role of traditional Chinese medicine and bioactive materials in chronic wound healing and reports no new clinical results.
4 citations
,
September 2020 in “Andrologia” This study found that Origanum vulgare extract improved testicular structure and function in mice against finasteride-induced damage by enhancing antioxidant defense and modulating gene expression related to apoptosis.
3 citations
,
January 2017 in “Journal of cosmetology & trichology” This study reports that a nutritional complex may improve hair density and quality, with in vitro findings demonstrating inhibition of 5α-reductase, and participants noting reduced hair loss and greasiness.
2 citations
,
January 2011 in “Andrologia” This study concluded that 16β-methyl-17α-benzoyloxypregnen-4-en-3,20-dione may be a promising treatment for androgen-dependent diseases and epilepsy due to its antioxidant effects and impact on GABAergic and serotonergic metabolism in rats.
June 2026 in “Discover Nano” This review discusses current treatment strategies for alopecia and highlights the potential of lipid-based nanoparticles to improve drug delivery to the scalp and hair follicles, noting their ability to enhance skin penetration and drug stability while outlining associated challenges and the need for further research.
This study reports that a novel ketoconazole-loaded microneedle array significantly enhances drug delivery and retention in the skin, demonstrating improved hair growth in animal models, suggesting a promising treatment for androgenic alopecia that addresses current topical therapies' limitations.
December 2025 in “Frontiers in Veterinary Science” This study found that PT-LCG extends hair follicle activity and promotes continuous cashmere growth by enhancing lipid synthesis, remodeling the extracellular matrix, and modulating inflammatory signaling, offering insights into improving cashmere yield and quality through molecular breeding.
July 2024 in “ADMET & DMPK” This review discusses the potential for surface-modified nanostructured lipid carriers to enhance hair regrowth by improving drug absorption and stability, focusing on their use with agents like minoxidil and finasteride for hair loss treatment.
October 2023 in “International Journal of Ayurvedic Medicine” The study observed that consuming Pflorida soup, made from UV-exposed oyster mushrooms, maintained significant vitamin D levels comparable to recommended daily intake, despite storage and cooking reducing the vitamin content.
September 2023 in “Asian journal of beauty & cosmetology” In this review paper, the authors explored the composition and role of lipids in human hair, highlighting their importance for hair texture, moisture retention, and tensile strength, while noting that the understanding of hair lipids' functions remains controversial and requires further research.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This pilot study suggests that a new preparation of platelet-rich plasma gel may improve symptoms and tissue regeneration in patients with en coup de sabre scleroderma, though further trials are needed to clarify its role.
21 citations
,
July 2017 in “Journal of Cosmetic and Laser Therapy” This review discusses the research and development of vesicular carriers to enhance the delivery and effectiveness of active ingredients in cosmetic products, reporting no new clinical results.
16 citations
,
December 2018 in “Plant Science” This study found that elevated carbon dioxide levels may help mitigate water deficit stress in soybean roots by altering gene expression related to stress and nutrient transport.
7 citations
,
October 2017 in “Artificial Cells Nanomedicine and Biotechnology” This research observed that finasteride-loaded ethosomes showed improved permeation across rat skin and human cadaver scalp skin compared to unencapsulated finasteride, potentially enhancing delivery to hair follicle units.
3 citations
,
October 2024 in “World Journal of Advanced Research and Reviews” This review highlighted the potential of silver nanoparticles' antibacterial properties across biomedical, pharmaceutical, and dental applications, and emphasized plant-based biosynthesis methods as eco-friendly alternatives to conventional nanoparticle production despite existing toxicity concerns.
451 citations
,
March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
130 citations
,
August 2020 in “Drug Design Development and Therapy” This review discusses various nanoparticles used to enhance skin permeation and target delivery to skin organelles, but reports no new experimental results.
127 citations
,
June 2006 in “International Journal of Pharmaceutics” This research found that liquid-state liposomes and niosomes may enhance finasteride delivery to pilosebaceous units in hamsters more effectively than gel-state vesicles or hydroalcoholic solution.
82 citations
,
January 2002 in “Journal of drug targeting” This study found that drug delivery through human scalp skin may be more effective for lipophilic and hydrophilic drugs compared to abdominal skin, highlighting the potential of intrafollicular delivery methods.
72 citations
,
December 2012 in “Expert Opinion on Drug Delivery” This review discusses niosomes' increasing popularity in dermatology for topical drug delivery due to their ability to enhance drug penetration, provide sustained release, and carry various drugs, while reporting no new clinical findings.
63 citations
,
March 2016 in “International Journal of Molecular Sciences” This review discusses the pathophysiology of sleep disturbance in children with atopic dermatitis and highlights the need for further research on management strategies, but provides no new clinical results.
58 citations
,
December 2012 in “Aaps Pharmscitech” This study suggests that finasteride-loaded liquid crystalline nanoparticles could be a viable alternative to oral administration for treating androgenetic alopecia due to their controlled release and skin permeation properties.
56 citations
,
January 2007 in “Pharmaceutical Development and Technology” This study found that finasteride-loaded liposomal formulations achieved significantly higher skin permeation and deposition compared to conventional gels and solutions, suggesting potential for effective topical application.
48 citations
,
December 2013 in “Drug Delivery and Translational Research” This study found that minoxidil-loaded niosomes with a Span 60 and cholesterol ratio of 1:2 significantly increased skin retention of minoxidil compared to control gel.
40 citations
,
June 2011 in “Journal of biological chemistry/The Journal of biological chemistry” This study revealed that deficiency in the enzyme FA2H in mice affected sebaceous gland function, altered sebum composition, and caused cycling alopecia, highlighting FA2H's role in hair follicle homeostasis.