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This paper reviews the role of androgens in human skin function and the challenges in developing treatments for androgen-associated disorders, reporting no new experimental results.

This review discusses the variability and limitations of treatments for severe alopecia areata, noting some patients may achieve cosmetic hair regrowth with treatment, while others experience persistent hair loss or relapse.

This review summarizes recent discoveries about how tissue-resident stem cells interact with their environments during normal conditions and after injury, without reporting new results.

This review discusses the evidence supporting Janus kinase inhibitors for alopecia areata and highlights ongoing optimism as phase 3 trials begin, with no new clinical results reported.

This review summarizes recent research on the molecular properties and functions of L-PGDS and PGD2, but reports no new findings, highlighting their pathophysiological roles and guiding future studies.

This study found that mice with a homozygous knockout of the Ten1 gene, developed through CRISPR-Cas9-mediated exon 3 deletion, exhibited telomere shortening and symptoms consistent with accelerated aging, such as reduced lifespan, skin changes, aplastic anemia, and cerebellar hypoplasia.

This review concluded that topical 5% Minoxidil treatment for androgenetic alopecia yielded the best results and enhancing it with other drugs or procedures further improved outcomes.

Platelet-rich plasma and stem cell therapies are accepted treatments for hair restoration, with specific protocols recommended for best results, but more standardization is needed in stem cell use.

This source does not report original research findings but reviews the mechanisms and challenges of immune response and immunosuppressive management in liver transplantation.

This review discusses the cornification process of epidermal keratinocytes in forming the skin barrier and reports no new results; it emphasizes the importance for diagnosis and treatment of skin disorders.

This research suggests that hair follicle-derived cytokines IL-7 and IL-15 are crucial for maintaining resident memory T cells in the skin, which may be relevant for diseases like cutaneous T cell lymphoma.

This study found that activating Wnt/beta-catenin signaling in hair follicles is sufficient to induce adipocyte generation in the dermis, affecting both hair follicle stem cell activation and adipocyte differentiation.

This study found that, while hair follicle bulge stem cells are important for hair follicle survival and epidermal regeneration after wounding, the epidermis maintains itself independently of these cells under normal conditions.

This review discusses the regeneration capabilities of various vertebrate tissues, focusing on the unique ability of certain species to regenerate teeth and lens, and reports no new results.

This study shows that alpha 6 + /MHCI - cells have gene expression profiles similar to hair follicle stem cells, suggesting they may be enriched for stem cells.

This study found that Secretory Phospholipase A2-IIA (sPLA2-IIA) promotes proliferation through JNK/c-Jun signaling, distinctively affecting normal stem cells and cancer cells, suggesting it as a potential target for cancer treatment.

This chapter reviews the presence and roles of stem cells in various body systems, focusing on their lifelong function in animals and humans, and reports no new experimental findings.

In this study, the authors concluded that the TS-associated polyomavirus may disrupt Wnt/β-catenin signaling, likely contributing to abnormal hair follicle formation in trichodysplasia spinulosa.

This review discusses the molecular mechanisms involved in hair follicle development and regeneration, highlighting findings from mouse genetic studies, and reports no new experimental results.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

This review highlights that alopecia areata is characterized by three immune endotypes, and while JAK inhibitors offer temporary control, upcoming multi-omics diagnostics and immune reprogramming strategies may achieve longer-lasting remission, according to this analysis.

This review discusses the roles of the hairless (HR) protein as a corepressor, particularly its impact on RORα-mediated transcriptional repression, and reports no new experimental findings.

The researchers reported that minor salivary gland stem cells exhibit stem cell characteristics and respond to tobacco-derived carcinogens, implicating the transforming growth factor beta pathway in their maintenance.

This study found that exosomes from human dermal papilla cell cultures, particularly in an oxygen-permeable 3D environment, most effectively supported hair follicle stem cell maintenance and promoted hair follicle formation in vitro.

This mini-review explores how both endogenous and damage-released RNAs serve as instructional signals that influence cell identity and plasticity during tissue maintenance and repair, highlighting RNA's role as a regulator of cellular flexibility in various regenerative contexts.

This review explores the physiological roles of collagen XVII in the epidermis, its involvement in stem cell maintenance, and its connections with signaling pathways, but it reports no new results.

In this study, Stat3 activation in transgenic mice led to a decrease in stem cells in the hair follicle bulge, suggesting its crucial role in epidermal growth and stem cell maintenance.

This chapter examines how toxins such as inorganic arsenic, dioxin, and bacterial toxins can disrupt the balance of keratinocyte stem cell regeneration and differentiation, affecting skin barrier maintenance.

This review explored the use of six tropical plants, such as Acacia concinna and Garcinia mangostana, as natural active ingredients in shampoos, highlighting their beneficial physicochemical properties and biological activities for hair care and scalp maintenance.

Stem-cell research shows promise for understanding and treating diseases.