2 citations,
September 2013 in “Journal of Cosmetic Dermatology” Hair restoration combines drugs and follicular unit grafting for natural, long-lasting results.
1 citations,
March 2024 in “Nanomaterials” Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
1 citations,
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
February 2024 in “Plastic and Reconstructive Surgery – Global Open” Stem cell therapies show promise for hair regrowth in androgenetic alopecia.
June 2023 in “Clinical Cosmetic and Investigational Dermatology” The new technique effectively treats hairline vitiligo with repigmentation and hair regrowth.
January 2022 in “Stem cell biology and regenerative medicine” 176 citations,
April 2011 in “Science” Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.
66 citations,
April 1995 in “The journal of cell biology/The Journal of cell biology” A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.
30 citations,
February 2018 in “Advanced Healthcare Materials” Nanoencapsulation creates adjustable cell clusters for hair growth.
26 citations,
July 2021 in “Frontiers in Cell and Developmental Biology” The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.
23 citations,
January 2018 in “International Journal of Molecular Medicine” Baicalin helps hair growth by activating specific cell signals and pathways.
5 citations,
January 2017 in “Molecular Medicine Reports” Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
5 citations,
September 2016 in “Dermatologic Therapy” Feily's method, which delays grafting for 24 hours to improve blood flow, successfully prevented scalp necrosis in three hair transplant patients.
2 citations,
October 2015 in “Human Gene Therapy” The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
2 citations,
May 2015 in “PloS one” Hair follicle pores help cell survival and growth, even after radiation.
1 citations,
April 2021 in “Current Stem Cell Reports” Eating less can improve stem cell function and increase lifespan.
June 2024 in “Regenerative Therapy” iPSCs show promise for hair regeneration but need more research to improve reliability and effectiveness.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
January 2023 in “Open veterinary journal” Cow blood vessel cell secretions helped heal rat burn wounds and may treat burns and hair loss.
June 2017 in “Journal of The American Academy of Dermatology” LED light helps hair follicle cells grow and prevents them from dying by activating certain cell pathways.
June 2017 in “Journal of The American Academy of Dermatology” LED light helps human hair root cells grow and move by activating certain cell pathways.
The study demonstrated that platelet-rich plasma (PRP) significantly promoted the viability and proliferation of human hair dermal papilla cells (HHDPCs) in vitro, particularly at a 5% concentration. PRP also increased the expression of alkaline phosphatase (ALP) and versican at both mRNA and protein levels. The study involved 8 healthy volunteers and used MTT assays, qRT-PCR, and Western blot analysis. These findings suggested that PRP could be a potential therapeutic tool for promoting hair follicle regeneration and treating alopecia, although further research is needed to identify the specific growth factors responsible for these effects.
Injecting a person's own skin cells back into their skin is a promising, safe, and affordable treatment for skin disorders.
550 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
132 citations,
February 2013 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
45 citations,
June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
4 citations,
July 2017 in “PubMed” Epidermal growth factor helps stem cells heal wounds and regenerate hair follicles faster.
2 citations,
June 2022 in “International Journal of Molecular Sciences” The study examined the expression of smooth muscle cell-related genes in human dermal sheath cup (DSC) cells and their impact on the outcomes of autologous cell-based therapy for male and female pattern hair loss, involving 32 DSC cell lines from 65 donors. It found that lower levels of smooth muscle cell markers like SRF and CALD1 were associated with better treatment outcomes. CHIR99021 treatment significantly downregulated these markers and upregulated SOX2 and LEF1, suggesting a shift towards dermal papilla cell properties, which are crucial for hair follicle generation. These findings indicate that modulating gene expression in DSC cells could enhance the efficacy of hair loss treatments. Further research with larger sample sizes is needed to validate these results.
207 citations,
April 2012 in “Development” Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
18 citations,
October 2014 in “Experimental Biology and Medicine” Eating vitamin A affects hair growth and health by changing cell signals in mice.