Search
for

    Glossary Cell Fate

    process determining cell's specialized function or type

    Cell fate refers to the final specialized function or type that a cell is destined to become during development. This process is influenced by various signals and environmental factors that guide the cell to differentiate into specific cell types, such as skin cells, nerve cells, or hair follicle cells. Understanding cell fate is crucial for fields like regenerative medicine and developmental biology, as it helps in manipulating cells for therapeutic purposes.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Mouse notch: expression in hair follicles correlates with cell fate determination. 1993 · 150 citations
    2. Cell fate decisions: emerging roles for metabolic signals and cell morphology EMBO Reports · 2017 · 100 citations
    3. Linking chromatin dynamics, cell fate plasticity, and tissue homeostasis in adult mouse hair follicle stem cells Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model · 2017 · 3 citations
    4. Spatiotemporal Switches in Progenitor Cell Fate Govern Upper Hair Follicle Growth and Maintenance Journal of Investigative Dermatology · 2025 · 2 citations
    5. Multi-scale modeling for cell fate specification during regeneration and development eScholarship (California Digital Library) · 2020
    6. Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate 2023 · 1 citations
    7. Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle Cell Metabolism · 2020 · 51 citations
    8. The Force Is Strong with This One: Metabolism (Over)powers Stem Cell Fate Trends in cell biology · 2018 · 33 citations
    9. <i>N</i>1-acetylspermidine is a determinant of hair follicle stem cell fate Journal of Cell Science · 2021 · 17 citations
    10. Epidermal stem cell fate: what can we learn from embryonic stem cells? 2007 · 15 citations
    11. Fibronectin meshwork controls epithelial stem cell fate bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 2 citations
    12. The Yin–Yang of Stress and Senescence: Integrated Stress Response and SASP Crosstalk in Stem Cell Fate, Regeneration, and Disease Biocell · 2025
    13. Signaling in the stem cell niche: regulating cell fate, function and plasticity Development · 2018 · 139 citations
    14. Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia Cell death and differentiation · 2012 · 19 citations
    15. Editorial: Directing Stem Cell Fate Using Plant Extracts and Their Bioactive Compounds Frontiers in Cell and Developmental Biology · 2022 · 4 citations
    16. Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture Nature cell biology · 2024 · 2 citations
    17. The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury Cell Metabolism · 2025
    18. The role of translation in keratinocyte cell fate determination. Apollo (University of Cambridge) · 2018
    19. 1349 Inducing fate changes at the hair follicle stem cell nice Journal of Investigative Dermatology · 2023
    20. Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis Genes & development · 2010 · 95 citations
    21. Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathway Stem cells · 2013 · 73 citations
    22. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate International Journal of Molecular Sciences · 2018 · 57 citations
    23. Neuregulin3 alters cell fate in the epidermis and mammary gland BMC developmental biology · 2007 · 39 citations
    24. Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate Genes · 2019 · 28 citations
    25. From structural resilience to cell specification — Intermediate filaments as regulators of cell fate ˜The œFASEB journal · 2020 · 9 citations
    26. A probabilistic Boolean model on hair follicle cell fate regulation by TGF-<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif"><mml:mrow><mml:mi>β</mml:mi></mml:mrow></mml:math> Biophysical Journal · 2022 · 5 citations
    27. Regulation of stem cell fate by HSPGs: implication in hair follicle cycling npj Regenerative Medicine · 2022 · 3 citations
    28. Hair follicle stem cell fate supports distinct clinical endotypes in hidradenitis suppurativa Journal of the European Academy of Dermatology and Venereology · 2025
    29. Developmental Mechanisms Controlling Cell Fate, Evolution of Elsevier eBooks · 2016
    30. Pgc-1α controls epidermal stem cell fate and skin repair by sustaining NAD+ homeostasis during aging Molecular Metabolism · 2022 · 22 citations