April 2011 in “한국생물공학회 학술대회” This study found that an anti-atopic lotion containing fucoidan helped heal skin damage in hairless mice with atopic dermatitis by reducing skin thickness and modulating immune responses.
February 2026 in “International Journal of Molecular Sciences” In this review, researchers discuss how mitochondria-targeted biophysical priming of autologous biologics, through methods like photobiomodulation and ultrasound, can potentially enhance skin rejuvenation and wound repair by modulating mitochondrial function in skin cells.
November 2025 in “Eurasian journal of applied biotechnology” In this study, combining L-cysteine and N-acetylcysteine with MET inhibition enhanced cytotoxicity in cancer cell lines by sensitizing them to MET inhibition through redox stabilization, suggesting a promising approach for improving MET-targeted cancer therapies without additional oxidative or chemotherapeutic stress.
127 citations
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January 2008 in “PloS one” This study observed that the vitamin D receptor is crucial for hair follicle formation and altering tumor development in the Wnt signaling pathway, suggesting therapeutic potential for vitamin D analogues in related tumors.
7 citations
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November 2020 in “Journal of Tissue Viability” In this study, follicular unit extraction grafting using a patient's own scalp follicles showed promise in healing chronic ulcers in a woman with recessive dystrophic epidermolysis bullosa.
1 citations
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December 2023 This study explored the complex developmental processes of human hair, emphasizing the intricate interactions required for hair follicle morphogenesis and its implications for drug incorporation and concentration interpretation, particularly in early childhood.
February 2026 in “Exploration” This review summarizes research on scar formation and inhibition mechanisms, discussing emerging therapies like gene therapy and stem cell treatments, but notes ongoing challenges for clinical application, including treatment personalization and outcome sustainability.
January 2026 in “Cosmetics” This study highlights emerging regenerative strategies, such as stem cell-derived therapies and machine learning tools, that may advance hair loss treatment beyond traditional methods by promoting follicle regeneration and offering personalized care.
December 2025 in “Pharmaceutics” This review highlights new perspectives in genomics and epigenomics for skin rejuvenation, comparing innovative strategies like senolytics and DNA repair modulators with classical treatments, and emphasizing the importance of tailoring therapies using individual genomic profiles for personalized anti-ageing approaches.
August 2024 in “Stem Cell Research & Therapy” This review discusses current and emerging therapies for androgenetic alopecia, emphasizing regenerative treatments and nanotechnology advancements, but it reports no new clinical results.
April 2024 in “Applied biological chemistry” In this study involving mice on a high-fat diet, piperine from black pepper was observed to reduce sebaceous gland size and fat accumulation, suggesting its potential in controlling hair oiliness by inhibiting adipogenesis in hair stem cells.
This study is the first to document significant age-related pathologies in endangered captive Julia Creek dunnarts, highlighting hormonal dysregulation and reproductive issues in females, while males exhibited higher occurrences of cutaneous diseases and testicular degeneration, providing valuable insight for conservation efforts.
This study identified significant differences in KIR gene profiles between SLE patients and controls, suggesting that specific KIR genes could serve as biomarkers for disease severity in Indian SLE patients.
July 2023 in “Bioengineering & translational medicine” This study explored a cell-free therapy with mesenchymal stem cell paracrine proteins and PEG hydrogels for deep burn treatment and found that the combination significantly enhanced wound healing, reduced scar formation, and promoted skin appendage regeneration in a rabbit model.
February 2026 in “International Journal of Molecular Sciences” This study found that PDLLA filler treatment may help combat age-related hair thinning by reducing oxidative stress and enhancing hair follicle function in both cell and animal models.
156 citations
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October 2012 in “Seminars in Cell & Developmental Biology” This study found that hair follicle stem cells initially contribute to wound re-epithelialization, but long-lasting epidermal cells are primarily derived from a stem cell population in the isthmus portion of hair follicles.
1 citations
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April 2021 in “Current Stem Cell Reports” This review discusses the role of metabolism in maintaining adult stem cell homeostasis with aging and highlights the potential benefits of dietary restrictions on stem cell function and longevity. It reports no new clinical results and emphasizes the need for further molecular studies.
January 2026 in “Preprints.org” This review highlights recent advancements in nanotechnology-based approaches for treating androgenetic alopecia, focusing on enhancing drug delivery to hair follicles, controlled release, and follicular microenvironment modulation, while addressing safety, manufacturing, and regulatory challenges for clinical application.
March 2024 in “Veterinary sciences” This study is the first to detail major geriatric diseases in aged Julia Creek dunnarts, particularly highlighting hormonal issues like cystic glandular hyperplasia in females and testicular degeneration in males, suggesting these conditions are linked to aging and potentially hormonal dysregulation.
87 citations
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August 2017 in “Scientific Reports” This study found that PCL-based nanofiber scaffolds enhanced cell proliferation and extracellular matrix deposition, suggesting they show promise as a cell delivery system for improving skin wound healing.
3 citations
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May 2022 in “Experimental Dermatology” This review discusses the role of hair follicle stem cell metabolism, ageing, and microenvironment in hair growth disorders and compiles recent research on using stem cell-based regenerative medicine for treating alopecia, without reporting new clinical results.
125 citations
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September 2019 in “Journal of Clinical Immunology” This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.
January 2024 in “Wiadomości Lekarskie” This paper reviews the development and implementation of CAR-T cell therapy as a significant advancement in treating pediatric hematological malignancies, particularly for children with relapsed or chemotherapy-resistant acute lymphoblastic leukemia, offering renewed remission prospects where conventional methods are ineffective.
January 1997 in “Medical Journal Armed Forces India” This study found that RADA-PRG hydrogels enhanced skin-derived precursor cell proliferation and improved hair follicle neogenesis in mice, suggesting potential use as a scaffold material in tissue engineering.
August 1994 in “Journal of dermatological science” Active oxygen scavengers can reverse the suppression of hair cell growth caused by androgens.
1 citations
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January 2020 This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.
In this study, researchers developed a mathematical model of outer hair cell hair bundles that replicates experimental responses to mechanical stimuli, providing insights into the stimulus-dependent adaptation mechanisms and the functional significance of their three-row stereocilia configuration in mammalian hearing.
53 citations
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July 2011 in “Biomaterials” This study observed that hepatocyte adhesion to human hair keratin biomaterials was mediated by the hepatic ASGPR, as blocking this receptor reduced cell attachment.
184 citations
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December 2018 in “Nature Communications” This study demonstrated that enhancing human skin constructs with hair follicles through engineered cell organization and vascularization improved hair growth in immunodeficient mice, suggesting potential advances for treating alopecia and chronic wounds.
46 citations
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September 2014 in “Tissue engineering. Part A” This study found that a 3D Matrigel culture technique for dermal papilla cell spheroids can enhance hair follicle inductivity and induce hair-like fiber differentiation in vitro, even with high-passage cells.