research Type-2 Immunity Associated With Type-1 Related Skin Inflammatory Diseases: Friend Or Foe?
Type-2 immunity may influence skin diseases and could be targeted for treatment.
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research Dermal Fibrosis in Male Pattern Hair Loss: A Suggestive Implication of Mast Cells
Mast cells might contribute to hair loss by causing skin thickening.
research Alopecia Areata: An Autoimmune Disease of Multiple Players
Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.
research Frontal Fibrosing Alopecia: A Comprehensive Review With Recent Updates
Frontal fibrosing alopecia is a challenging hair loss condition with no known cause or definitive treatment.
research The Role of Micronutrients in Alopecia Areata: A Review
People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.
research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions
PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
research Rare Cutaneous Side Effects of Imiquimod: A Review on Its Mechanisms, Diagnosis, and Management
Imiquimod can cause rare skin side effects, some irreversible, and long-term follow-up is important for users.
research Co-Localization of Alopecia Areata and Lichen Planopilaris in a Patient Receiving Immunosuppressants: A Rare Case
A woman on immunosuppressants developed two rare scalp conditions, which improved with specific treatments.
research Clinical Application of Nonantibiotic Macrolides for Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases
Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
research Cutaneous Reactions to Drugs
Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.
research PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia
PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
research Long-Term Outcome After Hand and Forearm Transplantation: A Retrospective Study
Hand and forearm transplants can be successful long-term, but they come with challenges like rejection and side effects from immunosuppression.
research Significance of Iron Status in Hair Loss in Women
Iron deficiency might contribute to hair loss in women.
research Causes and Management of Pica Disorder Among Central Iraqi Peoples
Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.
research The Role of the Skin Microbiome in Wound Healing
The skin microbiome helps heal wounds and can be targeted to improve healing.
research Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution, And Tumor-Initiating Cells
Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
research The Immune Response to COVID-19: Does Sex Matter?
Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.
research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–Like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Novel Advances of Histone Modification in Inflammatory Skin Diseases and Related Treatment Methods
Histone modification is key in treating chronic inflammatory skin diseases.
research Immunology of Alopecia Areata
Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
research Fibroblasts: Immunomodulatory Factors in Refractory Diabetic Wound Healing
Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
research Hair Follicles, Their Disorders, and Their Opportunities
Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
research Association of Autoimmune Regulator Gene Rs2075876 Variant, but Not Gene Expression, with Alopecia Areata in Males: A Case-Control Study
The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.
research Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy
Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.
research Discovery Of A Novel And Highly Selective JAK3 Inhibitor As A Potent Hair Growth Promoter
MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.
research Alopecia and Thyroid Disease
Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.
research COVID-19 Pandemic: What About the Gonads?
COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.
research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
research How Our Microbiome Influences the Pathogenesis of Alopecia Areata
Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.
research Two Cases of Alopecia Areata Treated with Ruxolitinib: A Discussion of Ideal Dosing and Laboratory Monitoring
Ruxolitinib effectively and safely regrows hair in alopecia patients.