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Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

The CD4 protein may play a role in the behavior of certain skin cells, affecting their growth, movement, and differentiation.

CD8+ T cells are involved in alopecia areata and may cause disease relapse.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Using healthy donor stem cells can potentially calm overactive immune cells and reduce inflammation in severe hair loss patients, offering a possible treatment method.

Cytotoxic T cells cause hair loss in chronic alopecia areata.

Severe alopecia areata involves higher levels of certain immune cells, which can be normalized with betamethasone.

ILC1-like cells can independently cause alopecia areata by affecting hair follicles.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

Potential therapeutic targets for scarring hair loss are identified.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

Regulatory T cells are essential for normal and improved wound healing in mice.

Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.

Symmetrical Acrokeratoderma (SAK) may be a unique skin condition in China, lacking specific treatment and needing long-term monitoring.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.

Blocking CCR5 can prevent and improve hair loss in alopecia areata.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.

Human hair follicles have a unique way of using energy and might use the Cori cycle; blocking CCR5 could help treat hair loss.

Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Transplant success has improved with better immunosuppressive drugs and donor matching.