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Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Dermatologists need to understand hair products to treat hair and scalp issues better.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.

Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.

Hedychium spicatum has medicinal properties but needs more research for scientific validation and use.

Late puberty may slightly lower prostate cancer risk, baldness is not linked to overall risk but less so with aggressive types, ibuprofen use may increase risk, and vitamins show no effect on risk.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.

Suppressing certain hormones might help prevent prostate cancer.