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Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.

The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

Activating TRPV3 stops human hair growth.

Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Tedisamil and glibenclamide affect cromakalim and minoxidil sulphate differently in rat aorta.

Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.

Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

Blocking TRPV3 may help treat itch in dry skin conditions.

Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

Certain essential oils can activate a human skin receptor, potentially helping with skin disorders.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.