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New treatments for male hypogonadism are effective and should be personalized.

Both mouse and rat models are effective for testing alopecia areata treatments.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

Manage side effects of hepatitis C treatment with dose changes and medications, which may improve patient adherence and treatment success.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Leptin helps start the growth phase of hair.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.

Bimatoprost increases hair growth in mice without breaking down into other substances.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

Different hormones affect hair growth and conditions, with some causing hair loss and others promoting it.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Hormones and genes affect hair growth and male baldness.

Apoptosis may contribute to hair loss in androgenetic alopecia.