24 citations,
August 2011 in “Experimental Dermatology” The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.
7 citations,
July 2020 in “Pigment cell & melanoma research” RT1640 treatment reverses gray hair and promotes hair growth in mice.
5 citations,
March 2016 in “Experimental and molecular pathology” Mice with alopecia areata had wider lymphatic vessels in their skin.
4 citations,
April 2011 in “International Journal of Radiation Biology” Radiation significantly slows down wound healing in mice.
7 citations,
May 2005 in “Experimental Dermatology” Two mouse mutations cause similar hair loss despite different skin changes.
56 citations,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
January 2024 in “Theranostics” HDAC6 helps keep ovarian follicles dormant, extending female fertility.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” miR-486 may help prevent hair loss in alopecia areata.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” HDAC inhibitors, like Vorinostat and Entinostat, can help regrow hair in alopecia areata.
9 citations,
January 2015 in “Laboratory Animal Research” Laminaria japonica and Cistanche tubulosa extracts combined may effectively promote hair growth.
50 citations,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
46 citations,
May 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Significant progress was made in understanding PXE, but effective treatments are still needed.
7 citations,
March 2022 in “The FASEB journal” Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
4 citations,
July 2019 in “Experimental Dermatology” 2-deoxy D-glucose does not help with hair regrowth in alopecia areata.
11 citations,
May 2022 in “Chinese medicine” Alpinetin helps grow hair by turning on hair stem cells and is safe for use.
7 citations,
November 2018 in “British Journal of Dermatology” Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.
March 2023 in “Biomedicine & Pharmacotherapy” GPR40 agonists help hair growth through the protein ANGPTL4.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Machine learning can predict how well patients with alopecia areata will respond to certain treatments.
22 citations,
October 2012 in “Journal of Investigative Dermatology” Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
19 citations,
February 2018 in “Lasers in Medical Science” Red light and LED treatments help hair grow by activating a specific cell signaling pathway.
December 2023 in “International journal of multidisciplinary research and analysis” SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
194 citations,
March 2003 in “American Journal of Pathology” Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.
108 citations,
July 2004 in “American Journal of Pathology” Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.
3 citations,
October 2010 in “Epilepsy Currents” Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Stress can cause a type of hair loss in mice lacking the CCHCR1 gene.
89 citations,
October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
January 2007 in “Elsevier eBooks” Alopecia areata is a reversible, autoimmune-related hair loss that can have significant emotional impact and uncertain treatment effectiveness.
15 citations,
September 2018 in “Hearing research” Rapamycin reduces age-related hearing cell loss in mice, but acarbose does not.
Whale oil significantly promotes hair growth and may be a safe, effective alternative to minoxidil.
9 citations,
January 2014 in “Molecular Genetics and Metabolism Reports” The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.